In silico prediction of B-cell epitopes of GroEL antigen from Brucella
Author:
, , , , , , , , ,Year
: 2014
Abstract: Brucellosis caused by bacterium Brucella, affecting various domestic and wild species. Economic and medical consequences
of this disease have led to efforts to prevent the infection through the use of vaccines. This study was conducted to predict Bcell
epitopes of GroEL as an important Brucella antigene. Three potential epitopes were predicted using bioinformatics tools
and were confirmed by 3D structure of Groel protein. This predicted epitopes may be suitable candidate for vaccine
production against Brocella.
of this disease have led to efforts to prevent the infection through the use of vaccines. This study was conducted to predict Bcell
epitopes of GroEL as an important Brucella antigene. Three potential epitopes were predicted using bioinformatics tools
and were confirmed by 3D structure of Groel protein. This predicted epitopes may be suitable candidate for vaccine
production against Brocella.
Keyword(s): Brucella,Epitope prediction,B-cell epitope,Vaccine production
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In silico prediction of B-cell epitopes of GroEL antigen from Brucella
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| contributor author | طوبی عباسی دلوئی | en |
| contributor author | مجتبی طهمورث پور | en |
| contributor author | محمدهادی سخاوتی | en |
| contributor author | سهیل یوسفی | en |
| contributor author | علی اکبر خبیری | en |
| contributor author | Tooba Abbassi Daloii | fa |
| contributor author | Mojtaba Tahmoorespur | fa |
| contributor author | Mohammad Hadi Sekhavati | fa |
| contributor author | Soheil Yousefi | fa |
| contributor author | Aliakbar Khabiri | fa |
| date accessioned | 2020-06-06T14:14:56Z | |
| date available | 2020-06-06T14:14:56Z | |
| date copyright | 5/20/2014 | |
| date issued | 2014 | |
| identifier uri | https://libsearch.um.ac.ir:443/fum/handle/fum/3388660?locale-attribute=en | |
| description abstract | Brucellosis caused by bacterium Brucella, affecting various domestic and wild species. Economic and medical consequences of this disease have led to efforts to prevent the infection through the use of vaccines. This study was conducted to predict Bcell epitopes of GroEL as an important Brucella antigene. Three potential epitopes were predicted using bioinformatics tools and were confirmed by 3D structure of Groel protein. This predicted epitopes may be suitable candidate for vaccine production against Brocella. | en |
| language | English | |
| title | In silico prediction of B-cell epitopes of GroEL antigen from Brucella | en |
| type | Conference Paper | |
| contenttype | External Fulltext | |
| subject keywords | Brucella | en |
| subject keywords | Epitope prediction | en |
| subject keywords | B-cell epitope | en |
| subject keywords | Vaccine production | en |
| identifier link | https://profdoc.um.ac.ir/paper-abstract-1042451.html | |
| conference title | پنجمین همایش بیوانفورماتیک ایران | fa |
| conference location | تهران | fa |
| identifier articleid | 1042451 |