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contributor authorحسین عشقیen
contributor authorمجید مکبر اصفهانیen
contributor authorمحمد رحیمی زادهen
contributor authorHossein Eshghifa
contributor authormajid mokaberfa
contributor authorMohammad Rahimizadehfa
date accessioned2020-06-06T14:10:31Z
date available2020-06-06T14:10:31Z
date copyright7/3/2013
date issued2013
identifier urihttps://libsearch.um.ac.ir:443/fum/handle/fum/3385577?show=full
description abstractIn recent years, significant interest has been devoted to the preparation of substituted indoles due to their varied biological activities including antioxidant, antibacterial, and insecticidal. They also act as colon cancer cell and tumor growth inhibitors and are employed as valuable antibiotics.[1,2]

Despite several methods available in the literature for the synthesis of substituted indoles, there are only a few reports on the access of substituted 3-aminoalkylated indoles using Multi Component Reactions (MCR) protocols.[3,4]

In this work three-component reactions of indoles, benzaldehydes and N-alkylanilines in the presence of an acid catalyst, such as ferric hydrogensulfate (FHS) as a recyclable, easy synthesized and inexpensive catalyst.(Scheme 1)

Decreasing of reaction times, increasing of isolated yields, low percent of bisindolylmethaneformation as byproduct and solvent free conditions are the benefits of this method by means of FHS as catalyst.
en
languageEnglish
titleOne-pot solvent free synthesis of someindolylmethane amine derivativesbyFe(HSO4)3 as a recycable catalysten
typeConference Paper
contenttypeExternal Fulltext
subject keywordsIn recent yearsen
subject keywordssignificant interest has been devoted to the preparation of substituted indoles due to their varied biological activities including antioxidanten
subject keywordsantibacterialen
subject keywordsand insecticidalen
subject keywordsThey also act as colon cancer cell and tumor growth inhibitoen
identifier linkhttps://profdoc.um.ac.ir/paper-abstract-1035436.html
conference title20th Iranian Seminar of Organic Chemistryen
conference locationهمدانfa
identifier articleid1035436


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