Effect of Acetylcysteine on Experimental Corneal Wounds in Dogs
Author:
, , , , , , ,Year
: 2003
Abstract: The effects of 3, 10 and 20% concentrations of acetylcysteine
on experimental corneal wound healing in dogs
were evaluated. Experimental corneal wounds were induced
surgically, up to the depth of the anterior third of
the stroma, in both eyes of 18 dogs. One of the eyes was
treated topically with 0.9% NaCl solution three times a
day. The contralateral eye was treated topically with acetylcysteine
(3, 10 and 20% concentrations) in each of 6
cases separately. Corneal wounds were measured by fluorescein
staining every day. The mean time of healing in
the 3% group was significantly different from control
eyes (6.17 B 1.94 days). It was 7.19 B 0.75 days in the
20% group and 7 B 2 days in the 10% group. The last
two groups were not significantly different from the
controls (9.67 B 3.01 days and 8.17 B 3.60 days, respectively).
on experimental corneal wound healing in dogs
were evaluated. Experimental corneal wounds were induced
surgically, up to the depth of the anterior third of
the stroma, in both eyes of 18 dogs. One of the eyes was
treated topically with 0.9% NaCl solution three times a
day. The contralateral eye was treated topically with acetylcysteine
(3, 10 and 20% concentrations) in each of 6
cases separately. Corneal wounds were measured by fluorescein
staining every day. The mean time of healing in
the 3% group was significantly different from control
eyes (6.17 B 1.94 days). It was 7.19 B 0.75 days in the
20% group and 7 B 2 days in the 10% group. The last
two groups were not significantly different from the
controls (9.67 B 3.01 days and 8.17 B 3.60 days, respectively).
Keyword(s): Acetylcysteine,Corneal ulcers,Wound healing
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Effect of Acetylcysteine on Experimental Corneal Wounds in Dogs
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| contributor author | Aldavood, S.J | en |
| contributor author | Behyar, R. | en |
| contributor author | علی اصغر سرچاهی | en |
| contributor author | Rad, M.A. | en |
| contributor author | Nroozian, I | en |
| contributor author | Ghamsari, S.M. | en |
| contributor author | Sadeghi-Hashjin, G. | en |
| contributor author | Ali Asghar Sarchahi | fa |
| date accessioned | 2020-06-06T13:15:56Z | |
| date available | 2020-06-06T13:15:56Z | |
| date issued | 2003 | |
| identifier uri | http://libsearch.um.ac.ir:80/fum/handle/fum/3348193?locale-attribute=en | |
| description abstract | The effects of 3, 10 and 20% concentrations of acetylcysteine on experimental corneal wound healing in dogs were evaluated. Experimental corneal wounds were induced surgically, up to the depth of the anterior third of the stroma, in both eyes of 18 dogs. One of the eyes was treated topically with 0.9% NaCl solution three times a day. The contralateral eye was treated topically with acetylcysteine (3, 10 and 20% concentrations) in each of 6 cases separately. Corneal wounds were measured by fluorescein staining every day. The mean time of healing in the 3% group was significantly different from control eyes (6.17 B 1.94 days). It was 7.19 B 0.75 days in the 20% group and 7 B 2 days in the 10% group. The last two groups were not significantly different from the controls (9.67 B 3.01 days and 8.17 B 3.60 days, respectively). | en |
| language | English | |
| title | Effect of Acetylcysteine on Experimental Corneal Wounds in Dogs | en |
| type | Journal Paper | |
| contenttype | External Fulltext | |
| subject keywords | Acetylcysteine | en |
| subject keywords | Corneal ulcers | en |
| subject keywords | Wound healing | en |
| journal title | Ophthalmic Research | fa |
| pages | 319-323 | |
| journal volume | 35 | |
| journal issue | 6 | |
| identifier link | https://profdoc.um.ac.ir/paper-abstract-1038419.html | |
| identifier articleid | 1038419 |