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Effect of Acetylcysteine on Experimental Corneal Wounds in Dogs

نویسنده:
Aldavood, S.J
,
Behyar, R.
,
علی اصغر سرچاهی
,
Rad, M.A.
,
Nroozian, I
,
Ghamsari, S.M.
,
Sadeghi-Hashjin, G.
,
Ali Asghar Sarchahi
سال
: 2003
چکیده: The effects of 3, 10 and 20% concentrations of acetylcysteine

on experimental corneal wound healing in dogs

were evaluated. Experimental corneal wounds were induced

surgically, up to the depth of the anterior third of

the stroma, in both eyes of 18 dogs. One of the eyes was

treated topically with 0.9% NaCl solution three times a

day. The contralateral eye was treated topically with acetylcysteine

(3, 10 and 20% concentrations) in each of 6

cases separately. Corneal wounds were measured by fluorescein

staining every day. The mean time of healing in

the 3% group was significantly different from control

eyes (6.17 B 1.94 days). It was 7.19 B 0.75 days in the

20% group and 7 B 2 days in the 10% group. The last

two groups were not significantly different from the

controls (9.67 B 3.01 days and 8.17 B 3.60 days, respectively).
یو آر آی: http://libsearch.um.ac.ir:80/fum/handle/fum/3348193
کلیدواژه(گان): Acetylcysteine,Corneal ulcers,Wound healing
کالکشن :
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    Effect of Acetylcysteine on Experimental Corneal Wounds in Dogs

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contributor authorAldavood, S.Jen
contributor authorBehyar, R.en
contributor authorعلی اصغر سرچاهیen
contributor authorRad, M.A.en
contributor authorNroozian, Ien
contributor authorGhamsari, S.M.en
contributor authorSadeghi-Hashjin, G.en
contributor authorAli Asghar Sarchahifa
date accessioned2020-06-06T13:15:56Z
date available2020-06-06T13:15:56Z
date issued2003
identifier urihttp://libsearch.um.ac.ir:80/fum/handle/fum/3348193?locale-attribute=fa
description abstractThe effects of 3, 10 and 20% concentrations of acetylcysteine

on experimental corneal wound healing in dogs

were evaluated. Experimental corneal wounds were induced

surgically, up to the depth of the anterior third of

the stroma, in both eyes of 18 dogs. One of the eyes was

treated topically with 0.9% NaCl solution three times a

day. The contralateral eye was treated topically with acetylcysteine

(3, 10 and 20% concentrations) in each of 6

cases separately. Corneal wounds were measured by fluorescein

staining every day. The mean time of healing in

the 3% group was significantly different from control

eyes (6.17 B 1.94 days). It was 7.19 B 0.75 days in the

20% group and 7 B 2 days in the 10% group. The last

two groups were not significantly different from the

controls (9.67 B 3.01 days and 8.17 B 3.60 days, respectively).
en
languageEnglish
titleEffect of Acetylcysteine on Experimental Corneal Wounds in Dogsen
typeJournal Paper
contenttypeExternal Fulltext
subject keywordsAcetylcysteineen
subject keywordsCorneal ulcersen
subject keywordsWound healingen
journal titleOphthalmic Researchfa
pages319-323
journal volume35
journal issue6
identifier linkhttps://profdoc.um.ac.ir/paper-abstract-1038419.html
identifier articleid1038419
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