structural modifications on their basic structure goes to new compounds with improved antibacterial activity such as ciprofloxacin and ofloxacin.[2]We focused on new functions that improved the antibacterial activity of these fluoroquinolones. Based...

such as fluoroquinolones cause mitochondrial dysfunction and decrease intracellular ATP level. The aim of this study was to compare the growth rate and migration potential of ciprofloxacin-resistant melanoma cells with ciprofloxacin-sensitive cells...

Herein, nucleophilic substitution reaction of pyrimidine derivatives on piperazine in ciprofloxacin resulted in the formation of new pyrimidyl N-ciprofloxacines. These compounds were prepared at room temperature, at conventional heating and under...

resistance. The aim of this study was to investigate the influence and the mechanism of ZnO NPs on the antimicrobial activity of ciprofloxacin (CP) and ceftazidime (CAZ) against Enterococcus faecalis (E. faecalis) and Acinetobacter baumannii (A. baumannii...

for overcoming bacterial resistance owing to their antibacterial activities. The aim

of this study was to investigate the combined effects of zinc oxide nanoparticles (ZnO-NPs) and the

conventional antibiotics ciprofloxacin and ceftazidime as well...

of the resulting ZnO nanofluid, ceftazidime, tobramycin, and ciprofloxacin were investigated against two P. aeruginosa strains, including one clinical isolate and P. aeruginosa ATCC 9027 using microdilution method. For the evaluation of the combined effect of Zn...

with ciprofloxacin -CIP- at a concentration of 5 μg mL-1 for two weeks. Exponentially grown cells in medium containing 5 μg mL-1 of CIP were designated as ciprofloxacin-resistant A375 cells and named A375-CIP5. MTT assay was used to investigate the cytotoxicity...

of ciprofloxacin -CIP-, a mitochondria-targeting antibiotic, on SB-590885-resistant BRAFV600E A375 melanoma -A375/SB- cells. The cytotoxicity activity of CIP and SB-590885, a potent and specific BRAFi, on A375 and A375/SB cells was evaluated by MTT, colony...

)- spermine conjugate on the antimicrobial activity of ceftazidime and

ciprofloxacin antibiotics against Enterococcus faecalis and Acinetobacter baumannii in acidic conditions.

Materials and Methods: Antibacterial activity of PMSA- spermine...

Introduction: Ciprofloxacin which was used in this study is a Fluoroquinolone (FQ). This

kind of drug may cause epileptic seizures probably because of the inhibition of GABA binding

to its receptors. Wag/Rij rats (an animal model...