Synthesis of a novel fused tricyclic heterocycle, pyrimido[5,4- e ][1,4]thiazepine, and its derivatives
نویسنده:
, , , , , , , ,سال
: 2013
چکیده: Sequential treatment of 5-bromo-2,4-dichloro-
6-(chloromethyl)pyrimidine with 2-aminothiophenol
and secondary amines afforded a series of 2-[(5-bromo-
2-chloro-6-aminopyrimidin-4-yl)methylthio]aniline derivatives.
Reaction of the latter compounds with secondary
amines in ethanol gave a family of new 5,7-diamino-
5,11-dihydropyrimido[5,4- e ][1,4]benzothiazepines.
6-(chloromethyl)pyrimidine with 2-aminothiophenol
and secondary amines afforded a series of 2-[(5-bromo-
2-chloro-6-aminopyrimidin-4-yl)methylthio]aniline derivatives.
Reaction of the latter compounds with secondary
amines in ethanol gave a family of new 5,7-diamino-
5,11-dihydropyrimido[5,4- e ][1,4]benzothiazepines.
کلیدواژه(گان): [5,4- e ][1,4]benzothiazepines,nucleophilic substitution,
secondary amines,1,4-thiazepine
کالکشن
:
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آمار بازدید
Synthesis of a novel fused tricyclic heterocycle, pyrimido[5,4- e ][1,4]thiazepine, and its derivatives
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| contributor author | تهمینه بزازان نوغانی | en |
| contributor author | مهدی بکاولی | en |
| contributor author | محمد رحیمی زاده | en |
| contributor author | حسین عشقی | en |
| contributor author | M. Nikpour | en |
| contributor author | tahmineh bazazan noghani | fa |
| contributor author | Mehdi Bakavoli | fa |
| contributor author | Mohammad Rahimizadeh | fa |
| contributor author | Hossein Eshghi | fa |
| date accessioned | 2020-06-06T13:37:16Z | |
| date available | 2020-06-06T13:37:16Z | |
| date issued | 2013 | |
| identifier uri | https://libsearch.um.ac.ir:443/fum/handle/fum/3362302?locale-attribute=fa | |
| description abstract | Sequential treatment of 5-bromo-2,4-dichloro- 6-(chloromethyl)pyrimidine with 2-aminothiophenol and secondary amines afforded a series of 2-[(5-bromo- 2-chloro-6-aminopyrimidin-4-yl)methylthio]aniline derivatives. Reaction of the latter compounds with secondary amines in ethanol gave a family of new 5,7-diamino- 5,11-dihydropyrimido[5,4- e ][1,4]benzothiazepines. | en |
| language | English | |
| title | Synthesis of a novel fused tricyclic heterocycle, pyrimido[5,4- e ][1,4]thiazepine, and its derivatives | en |
| type | Journal Paper | |
| contenttype | External Fulltext | |
| subject keywords | [5 | en |
| subject keywords | 4- e ][1 | en |
| subject keywords | 4]benzothiazepines | en |
| subject keywords | nucleophilic substitution | en |
| subject keywords | secondary amines | en |
| subject keywords | 1 | en |
| subject keywords | 4-thiazepine | en |
| journal title | Heterocyclic Communications | fa |
| pages | 401-404 | |
| journal volume | 19 | |
| journal issue | 6 | |
| identifier link | https://profdoc.um.ac.ir/paper-abstract-1065251.html | |
| identifier articleid | 1065251 |