Influence of Selected Exercise on Serum Immunoglobulin, Testosterone and Cortisol in Semi-Endurance Elite Runners

Abstract

Abstract<br><br>Purpose: The aim of this study was to compare the levels of serum<br><br>immunoglobulin (IgA, IgM, IgG), testosterone and cortisol in semi-endurance<br><br>elite runners during general preparation and competition phase of training.<br><br>Methods: Thirteen semi-endurance elite male runners with an average age of<br><br>18.92±1.7 years volunteered to take part in this study. The runners participated<br><br>in the selected training for a period of 14 weeks and 12 seasons per a week (in<br><br>the morning and afternoon). Blood samples were collected during the three<br><br>phases of training (before-preparation phase, after-preparation phase and<br><br>before-competition phase). Data were analyzed by repeated measures and<br><br>Bonferroni post hoc test, at a significance level of P&lt;0.05.<br><br>Results: The levels of serum IgM in semi-endurance elite runners after<br><br>preparation phase reduced significantly (P=0.004), while these levels during the<br><br>competition phase increased even though significantly. The levels of serum IgG<br><br>and IgA also reduced, however not significantly, during both phases. Moreover,<br><br>after preparation phase, there was no significant change in serum IgA levels;<br><br>though, these levels reduced, however not significantly, before competition<br><br>phase. Cortisol levels significantly decrease after preparation phase (P=0.04);<br><br>although, it increased before competition phase. Testosterone/cortisol ratio<br><br>increases significantly after preparation phase (P=0.04), and it decreased before<br><br>competition phase. Testosterone levels intangibility increased and decreased<br><br>respectively after preparation and before competition phases.<br><br>Conclusions: Findings indicated that long and intensive exercises weaken the<br><br>immune system, while moderate and short drills strengthened this system.