Abstract: This study reports the synthesis of steroidal quaternary ammonium compounds 11 and 12, with quaternary nitrogen at position 3 and 16 of the steroid nucleus in 5a-epiandrosterone series; along with their neuromuscular blocking activity...

Quaternary ammonium compounds are generally known to be bioactive substances and are used

mainly for environmental disinfection, disinfection of medical equipment, and disinfection in

hospitals. The mode of antimicrobial action...

using ammonium sulfate, and the active enzyme was purified by Q-sepharose ion exchange chromatography.The enzyme activity was reached to 200 U/ml after 48 h incubation in culture medium. The enzyme was quite stable in diffrent temperature...