to improve the immunoprotective effects and safety of vaccines against Brucella. This study was designed to evaluate the immunogenicity of DNA vaccines encoding B. melitensis outer membrane proteins (Omp25 and Omp31) against B. melitensis Rev1 in a mouse...

-linked

immunosorbent assay in 12 groups (individual and simultaneous injections of rOMP25 and

rOMP31 in different protein concentrations) and lymphocyte proliferation was measured

using 3–4,5-dimethylthiazol-2-yl2,5-diphenyltetrazolium bromide (MTT) assay based...

Brucellosis is a well known infection among domestic animals caused by Brucella bacterium. The objective of the present study was to clone, sequence analysis and epitopes prediction of Omp31 and Omp25 genes as major B. melitensis antigens. Up...

the use of recombinant vaccines based on Brucella outer mem-brane protein (OMP) antigens. In the present study, a wide range of on-line prediction software was used to predict B and T-cells epitopes, secondary and tertiary tructure and antigenicity OMP25...

, and the Middle East have currently been listed as high-risk regions. The genus Brucella is classified in at least nine species. Brucella melitensis is the global pathogenic species of Brucella. The outer membrane protein 31, (Omp31) from B. melitensis...

بیماری بروسلوز به عنوان یک بیماری مشترک بین انسان و دام به واسطه تکثیر باکتری بروسلا در داخل سلول‌های پستانداران اتفاق می‌افتد. Omp31 یکی از پروتئین‌های غشای خارجی این باکتری می‌باشد که به واسطه نقش مهمی که در تحریک سلول‌های CD8+ T و CD4+ T دارد می‌تواند...

Brucellosis is a zoonotic disease in human and animals. Brucella melitensis is one of the most pathogenic

species of Brucella in goat and sheep. Omp31 is an outer membrane protein of Brucella that acts as an

immunogenic protein...

Brucella melitensis, as a pathogenic gram-negative intracellular bacterium, causes brucellosis in animals and humans. According to literature, the B. melitensis outer membrane protein 31 (Omp31) is considered as an important vaccine candidate...

پروتئین OMP55 یکی از آنتیژنهای خارج غشائی باکتری بروسلا است که دارای ویژگیهای آنتیژنیک میباشد. این آنتیژن یکی از

آنتیژنهای اصلی است که نقش مهمی در ایجاد بیماری بروسللوز و همچنلین زنلده ملا نی بلاکتری بروسللا دارد . در ایلن ماالعله ژن

OMP...