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RISInvestigating the Genotoxic Effect of Gamma Irradiation on L929 Cells after Vinblastine Treatment Using Micronucleus Assay on Cytokinesis-blocked Binucleated Cells
There are several studies suggesting the role of aneuploidy in tumor formation. Aneuploid cells are different from normal ones in term of gene expression and proteome. Cells with different amount and kind of proteins might ...
Investigating the Vinblastine Induced-Chromosomal Abnormality in the Already Gamma Irradiated L929 Cell Line Using Micronucleus Assay in Cytokinesis Blocked Binucleated Cells
Objectives: Vast number of studies show the relationship between aneuploidy and cancer. Ionizing radiation in addition to induce all kinds of damages to the cells and structure of chromosomes, is also able to induce ...
Origanum vulgare leaf extract protects mice bone marrow cells against ionizing radiation
Objective: Ionizing radiation produces free radicals which induce DNA damage and cell death. Origanum vulgare leaf extract (OVLE) is a natural compound and its capability of scavenging free radicals and its antioxidant ...
Investigating the Effect of Gamma Irradiation on Vinblastine-Induced Aneuploid L929 Cell Lines Using Micronucleus Assay on Binucleated Cells
Cancer, as one of the most important concerns of human health, is an illness with genetic
cause. There are various theories to explain how it originates. Genetic and phenotypic
instability are two known ...
Investigating the Genotoxic Effect of Gamma Irradiation on L929 Cells after Vinblastine Treatment Using Micronucleus Assay on Cytokinesis-blocked Binucleated Cells
بررسی اثر زنوتوکسیک تابش اشعه گاما بر رده سلولی L929 پس از تیمار با وین بلاستین با استفاده از آزمون میکرونوکلئوس در سلول های دو هسته ای
مطالعات زیادی نقش آنیوپلوئیدی در سرطان را پیشنهاد می کنند. سلول های آنیوپلوئید از نظر بیان ژنی و محتوی پروتئینی با سلول های سالم متفاونپتند. سلول های با انواع و مقادیر مختفاوت پروتئینی ممکن است به محرک های بیرونی مانند ...