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بررسی اثرات سمیت سلولی 2-(4-متوکسی فنیل)-بنزایمیدازول بر روی سلول های سرطان پستان در شرایط in vitro
مقدمه: با وجود روش های درمانی مختلف برای مقابله با سرطان، بزرگترین مانع در راه درمان سرطان های متاستاتیک مثل سرطان پستان، این است که به طور ذاتی به شیمی درمانی مقاوم هستند و یا در طول شیمی درمانی به دارو مقاوم می شوند. ...
Investigating the Regenerative Potential of Trans- differentiated Adipose-derived Stem Cells (t-ASCs) in Cutaneous Wound Healing
Cutaneous wound healing is a complex type of biological event involving proliferation, differentiation, reprograming, trans/de-differentiation, recruitment, migration, and apoptosis of a number of cells (keratinocytes, ...
مقایسه استحصال و موفقیت در تخلیص سلول های بنیادی مزانشیمی از دو منبع بافت استخوان و بافت چربی انسان
مقدمه: سلول های بنیادی مزانشیمی (MSCs: Mesenchymal stem cells) با داشتن مزیت هایی نظیر قابلیت توان تمایزی و اعمال آثار پاراکراین در درمان بیماری های مختلف نقش دارند. لذا استفاده از MSCs به عنوان ابزاری در سلول درمانی، ...
HYPOXIA-MIMICKING AGENTS PROMOTE CXCR4 GENE EXPRESSION AND MIGRATION OF MESENCHYMAL STEM CELLS TOWARDS SDF1
Despite that exploration of potential clinical sources of mesenchymal stem cells (MSCs) is giving rise into great promise in the field of regenerative medicine, proper homing is still a prerequisite to exhibit any type of ...
Use of Stromal Amniotic Membrane as a Suitable Scaffold for Tissue Engineering
Objective: The amniotic membrane (AM) is the innermost layer of the placenta and has unique biological and mechanical properties that make it a good biomaterial for tissue engineering. AM possesses most characteristics ...
Markers of Pluripotency Can be Induced in Human Keratinocytes after Co-culturing with a Pluripotent Tissue
Objective: Stem cells are found in various tissues and under certain physiological or experimental conditions, they can be induced to differentiate into other cell types. Based on their origin, they can be divided into two ...
Evaluating the in vitro toxicity of a benzo[d]imidazole derivative on 5637 cells
Introduction: The main histological form of bladder cancer is transitional cell
carcinoma (TCC) which is considered as the second most common urological
malignancy after prostate cancer. Although various ...