Stem/progenitor cell based therapeutic approach in our daily routine clinical practice, has been

elusive dream in medical sciences and improve

ment of stem cell homing as one of major challenges

in ...

Objective: Canceris known as one of the most challenging diseases in management and therapy, especially in developing countries. In Iran, for instance, high mortality of gastrointestinal malignancies, including Esophageal ...

Induced pluripotent stem cells are generated by direct reprogramming of somatic cells with the introduction of defined

transcription factors or other means. Clinical applications of induced pluripotent stem cells ...

Introduction: According to the National Institute of Health (NIH) it is estimated that 80 to 90 percent of potential therapeutics in preclinical testing runs into obstacles that prevent them from being translated to the ...

استفاده از توالی های اینترونی در تشخیص و درمان بیماری های ژنتیکی، از جمله کاربردهای این توالی های غیر کدگذار ژنومی می باشد که پس از شناخت

نقش تنظیمی آنها قوت گرفته و تائید شده است. نقش تنظیمی این توالی های بزرگ می ...

Cutaneous wound healing is a complex type of biological event involving proliferation, differentiation, reprograming, trans/de-differentiation, recruitment, migration, and apoptosis of a number of cells (keratinocytes, ...

The rise in the incidence of obesity and diabetes has increased the burden of treating chronic wounds. Burn injuries also affect 11 million people worldwide annually. In addition, postsurgical wound cares are not cost ...

Regeneration is a biological phenomenon, which takes place via two main mechanisms: first,

dedifferentiation of mature cells followed by their differentiation into functional new cells and second,

activation ...

مقدمه: سلول های بنیادی مزانشیمی (MSCs: Mesenchymal stem cells) با داشتن مزیت هایی نظیر قابلیت توان تمایزی و اعمال آثار پاراکراین در درمان بیماری های مختلف نقش دارند. لذا استفاده از MSCs به عنوان ابزاری در سلول درمانی، ...

Cell Stemness can be achieved by various reprogramming techniques namely, somatic cell nuclear transfer, cell fusion, cell extracts, and introduction of transcription factors from which induced pluripotent stem cells (iPSCs) ...