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Thiazolo[4,5- d ]pyrimidines: synthesis and antibacterial evaluation
Year: 2011
Abstract:
The reaction of 4-amino-5-bromo-2-chloro-6-methylpyrimidine
( 1 ) with carbon disulfi de in the presence of KOH in
DMF quantitatively gave 5-chloro-7-methylthiazolo[4,5- d ]
pyrimidine-2 (3 H )-thione ...
New access to thiazolo[4,5-d]pyrimidine derivativess
Year: 2006
Abstract:
with various isothiocyanates in the presence of sodamide in DMF to form the new thiazolo[4,5-d] pyrimidine derivatives....