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RISOzone inhalation can induce chromosomal abnormalities in bone marrow cells of wistar rats
use of ozone, the human could be more and more exposed to this gas. In this study the effects of ozone inhalation on chromosomes and its clastogenic consequences have been investigated using in vivo micronucleus assay in bone marrow cells of treated...
Hydrocortisone increases the vinblastine-induced chromosomal damages in L929 cells investigated by the micronucleus assay on cytokinesis-blocked binucleated cells
-treated cells. The induced chromosomal damages were investigated by micronucleus assay in cytokinesis-blocked binucleated cells.
Results: Although HYD by itself did not increase the micronuclei (Mn) frequency, co-treatment of cells with VIN and HYD led...
Investigating the Genotoxic Effect of Gamma Irradiation on L929 Cells after Vinblastine Treatment Using Micronucleus Assay on Cytokinesis-blocked Binucleated Cells
were investigated using micronucleus -Mn- assay. Data showed that vinblastine and gamma irradiation both were able to significantly increase micronucleated-binucleated cells -MnBi- frequency. However, 1 Gy gamma irradiation of the cells after 72 h...
Investigating the Vinblastine Induced-Chromosomal Abnormality in the Already Gamma Irradiated L929 Cell Line Using Micronucleus Assay in Cytokinesis Blocked Binucleated Cells
from the harmful effect of irradiation. They were treated with low dose of vinblastine (0.5 ng.ml-1) 72h post-gamma irradiation. Finally, the induced chromosomal abnormalities were scored using micronucleus assay in cytokinesis-blocked binucleated cells...
Investigating the Effect of Gamma Irradiation on Vinblastine-Induced Aneuploid L929 Cell Lines Using Micronucleus Assay on Binucleated Cells
1Gy of gamma radiation after 72 hours of vinblastine treatment. In all part of the experiment
cells were harvested 24 hours after cytochalasin B treatment. Induced-chromosomal
damages were investigated using micronucleus assay...
بررسی صحت تقسیم سلولی در سلولهای ناتوان در تعمیر DNA
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Investigating the Genotoxic Effect of Gamma Irradiation on L929 Cells after Vinblastine Treatment Using Micronucleus Assay on Cytokinesis-blocked Binucleated Cells
بررسی اثر زنوتوکسیک تابش اشعه گاما بر رده سلولی L929 پس از تیمار با وین بلاستین با استفاده از آزمون میکرونوکلئوس در سلول های دو هسته ای
مطالعات زیادی نقش آنیوپلوئیدی در سرطان را پیشنهاد می کنند. سلول های آنیوپلوئید از نظر بیان ژنی و محتوی پروتئینی با سلول های سالم متفاونپتند. سلول های با انواع و مقادیر مختفاوت پروتئینی ممکن است به محرک های بیرونی مانند ...
اثر چای سبز در مهار آسیب های کروموزومی القایی امواج تلفن همراه ( 940 مگا هرتز) بر اریتروسیت های پلی کروماتیک مغز استخوان موش نر بالب سی
زمینه و هدف: چای سبز با خواص آنتی اکسیدانی خود می تواند از بروز برخی آسیب های کروموزومی جلوگیری کند. در ژوهش حاضر اثر چای سبز در مهار آسیب های کروموزومی القایی توسط امواج تلفن های همراه (امواج تلفن های همراه به دت 4 روز، ...
Study of radioprotective effect of green tea against gamma irradiation using micronucleus assay on binucleated human lymphocytes
samples were exposed to 200 cGy of 60 Co gamma irradiation and then cultured with mitogenic stimulation to determine the chromosomal aberration in micronucleus assay on cytokinesis-blocked binucleated cells.
Results:
For each volunteer...
Analysing the Radioprotective Effect of Cotoneaster Nummularia in Mouse Bone Marrow Cells Using Micronucleus Assay
, against 2 Gy Gamma irradiation, was analyzed using micronucleus assay on bone marrow cells of male mice (Balb/c). Different doses of 250, 500, 1000 mg/kg/BW for aqueous and 3750, 7500, 15000 mg/kg/BW for alcoholic extract of Shirkhesht were administered IP...