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RISNeutrons applications in cancer treatment and in specific diagnostics
The major effect of ionizing radiation in cells is to destroy the
ability of cells to divide by damaging their DNA strands. Extensive
researches are leading to an understanding that the characteristics
of ...
Use of bacterial ghosts as novel drug delivery systems to improve cancer treatment
Introduction: The bacterial ghost (BG) system represents a novel
and progressive approach in the development of bacterial mediated
cancer immunotherapy. The empty inner space of BGs can be filled
with ...
Glutathione mediated release of functional MiR 122 from gold nanoparticles for targeted induction of apoptosis in cancer treatment
Surface functionalized mesoporous silica nanoparticles as an effective carrier for epirubicin delivery to cancer cells
Recent studies with inorganic nanoparticles modified with functional groups have demonstrated
improvement in drug delivery into cancer cells. In the present study, we prepared, characterized, and
evaluated ...
Co-Delivery of Epirubicin and siRNA Using Functionalized Mesoporous Silica Nanoparticles Enhances In vitro and In vivo Drug Efficacy
Development of drug resistance to anticancer drugs is an important challenge for cancer treatment. Recent studies focus on co-delivery of anticancer drugs and siRNA to overcome this challenge. Mesoporous silica nanoparticles (MSNs) are one...
Engineering of bovine pancreatic ribonuclease to induce apoptosis in cancer cells
Ribonucleases (RNase) are responsible for the degradation of RNA. RNase are a superfamily of
enzymes which catalyze the degradation of RNA into smaller components. These enzymes can be
potentially cytotoxic ...
Preparation and characterization of mesoporous hydroxyapatite thin film and evaluation of its osteogenic properties
Hydroxyapatite is a calcium phosphate with the formula Ca10(PO4)6(OH)10 and it is the main
constituent of mineral phase of bone. This biomaterial is widely used after bone tumor surgery for
treatment of bone ...
Tumor paint a method to improve brain cance surgery
It has been estimated that brain tumors are the second most common cancers in children and are 25% of all tumors in adults. They are the most lethal cancers, grow rapidly and invade the surroundinghealthy brain tissue. ...
Theraputic targeting of cancer stem cells 1.
Cancer stem cells (CSCs) are a minor subset of chemotherapy-resistant and radiotherapy-resistant
tumor cells that can undergo unlimited self-renewal and generate tumor mass. CSC-targeted therapies
are more ...