BACKGROUND: Cancer stem cells (CSCs), also known as tumour initiating cells, are highly

proliferating cancerous cells that have been found in several kinds of leukemia and solid tumours.

CSCs are likely to share many of the properties...

of tumourigenic cancer stem cells have

escaped the normal limits of self-renewal giving rise to abnormally differentiated cancer

cells that contribute to tumour progression and growth. The cancer-initiating cells or cancer

stem cells were...

Cancer stem cells are a population of self-renewing stem cells, which are present

in most, if not all, tumours. Teratocarcinomas are a type of germ cell tumours that provide a

paradigm of stem cell concept of cancer...

Stem Cells (SCs), with their ability to produce different types of cell can also work as fantastic repairing agents. Similar to

SCs, there are a certain type of cancer cell which called Cancer Stem Cells (CSCs). These cells are the reproducer...

Cancer remains a major cause of death worldwide. Huge research and identification of several markers have resulted in better understanding of its mechanism. Researches focusing on cancer stem cells and their role in metastasis will help...

recurrence and metastasis of malignant cells. Cancer stem cells (CSCs) are undifferentiated and highly proliferative malignant cells with unique properties mediated by overexpression of stemness markers, metastasis-related proteins, drug transporters...

Cancer stem cells (CSCs) are a subpopulation of

tumour cells that possess the stem cell properties of selfrenewal

and differentiation. Stem cells might be the target

cells responsible for malignant transformation, and tumour...

on the expression pattern and biological function of BORIS in normal, as well as cancer cells/tissues, and presents some evidence that support the expression of BORIS in cancer stem cells (CSCs) and advanced stage/poorer diferentiation grade of cancers. Boris...

inherent chemotherapy resistance, 3) its well-stablished role in different cellular functions, 4) complicated interaction with

other signaling pathways and 5) a lack of effective targeted therapy. Cancer stem cells found within tumors have the ability...

Introduction: Cancer stem cell (CSC) hypothesis was first proposed in acute myeloid leukemia and it has been demonstrated that solid human tumors such as liver cancer also contain CSCs. These cells are a small subpopulation of cells responsible...