A novel approach to synthesis of new imidazo[2',1':2,3]thiazolo[5,4-d]pyrimidines as a class of heterocyclic compounds

Abstract

we have presented an efficient synthetic pathway for the synthesis of new derivatives of imidazo[2ˈ,1ˈ:2,3] thiazolo[5,4-d]pyrimidin 4(a-g) via the heterocyclization of 2,5-dichloro-7-methylthiazolo[5,4-d]pyrimidine (1) with glycine. The foregoing tricyclic heterocyclic derivatives can be useful templates in drug discovery