Punica granatum peel: an organocatalyst for green and rapid synthesis of 3,4-dihydropyrimidin-2 (1H)-ones/thiones under solvent-free condition

Abstract

A novel and green approach was adopted for the synthesis of 3,4-dihydropyrimidin-2(1H)-one/thiones derivatives using Punica granatum peel as an inexpensive, efficient and mild catalyst under solvent-free condition. The methodology is characterized by high efficiency, short reaction time, high yields, simple<br><br>experimental procedure, availability of catalyst and environmentally friendly reaction conditions. Further, the catalyst can be reused and recovered seven times without significant decrease in its activity.