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RISPretreatment of mesenchymal stem cells and stromal - derived factor - 1α delivery from chitosan - based injectable hydrogels for better cell guidance and retention
Abstract:
Clinical applications of mesenchymal stem cells (MSCs) rely on their capacity to home and engraft in
the appropriate target tissues for a long time. Homing and engraftment capacity of these stem ...
Long bone mesenchymal stem cells (Lb-MSCs): clinically reliable cells for osteo-diseases
Mesenchymal stem cells (MSCs) have been designated as the most reliable cells in clinics to treat osteo-diseases because of their versatile nature. MSCs, isolated from long bone (Lb-MSCs) are rarely reported and named as ...
Evidence for crossing the blood barrier of adult rat brain by human adipose-derived mesenchymal stromal cells during a 6-month period of post-transplantation
Background aims. Therapeutic promises of adult stem cells have been overshadowed by an elicited immune response, low maintenance of implanted cells or concerns regarding their migration to non-target sites. These problems ...
Human adipose-derived mesenchymal stem cells can survive and integrate into the adult rat eye following xenotransplantation
Background: Novel threads of discovery provide the basis for optimism for the development of a stem-cell-based strategy for the treatment of retinal blindness. Accordingly, achievement to suitable cell source with ...
Injectable hydrogel delivery plus preconditioning of mesenchymal stem cells: exploitation of SDF-1/CXCR4 axis toward enhancing the efficacy of stem cells’ homing
therapeutic outcomes in stem cell therapy....