In spite of major advances in cancer chemotherapy, effective response is obtained only in a small

proportion of patients, which is due to acquired drug resistance of cancer cells. Ferula species are good

sources of sesquiterpenes...

Chemical composition antibacterial activity and cytotoxicity of essential oil from Nepeta ucrainica L. spp. kopetdaghensisAbolfazl

Herbal Medicineshave been widely considered in recent decades due to the publication of numerous studies and researches on medicinal herbs and their active compounds,which suggests having great properties and different treatment features.Sesquiterpene...

cells are

resistant to some chemotherapeutic agents such as vincristine (VCR). In the present

study, the effect of feselol, a sesquiterpene coumarin isolated from the fruits of Ferula

badrakema, was investigated on VCR effectiveness...

Drug combination is often applied to increase the effectiveness of treatment for specific and severe illnesses, such as cancer. So far various approaches have been designed to identify the effects of each drug when used ...

to cisplatin limit its effectiveness. The aim of this study was to determine the ability

of mogoltacin, a sesquiterpene-coumarin from Ferula badrakema, to enhance cytotoxic effects of cisplatin

on 5637 cells, using MTT assay, comet method, DAPI...