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RISSynthesis of Thiazino[2,3-b]quinoxaline as a New Heterocyclic System
species and extended π-conjugation facilitate in
decreasing columbic repulsion [1]. Quinoxalines and thiazines are important heterocycles
in medicinal chemistry [2,3].Quinoxaline is one of the benzo-fused six...
One-pot, procedure for the preparation of some thiazino[2,3-b]quinoxaline derivatives
An efficient and convenient synthesis of new thiazino[2,3-b]quinoxaline derivatives has been developed by employing a one-pot cyclo-condensation of several α-haloketones and 3-aminoquinoxaline-2-thiol in acetic acid. A similar reaction with 4‑bromo...
Synthesis and Complexing Properties of Novel Crown Ethers and Thiacrown Ethers Incorporating New Heterocyclic Moieties
The synthesis of some novel crown and thiacrown ethers via the reaction of 2,3-bis(4-
hydroxyphenyl) or 2,3-bis(4-mercaptophenyl)quinoxalines and pyridopyridazine with diethylene
and triethylene glycol ditosylate is described...
Synthesis of pyrimido [4′,5′:5,6] [1,4] dithiepino [2,3- b] quinoxalines: Derivatives of a novel seven membered ring system
A convenient and efficient procedure for the synthesis of tetracyclic dithiepin derivatives is described
through the condensation reaction of 2,4-dichloro-5-(chloromethyl)-6- methylpyrimidine and quinoxaline-
2,3-dithiol followed...
Synthesis of 2-substituted-4-methyl-5,13- dihydropyrimido[4',5':5,6][1,4]thiazepino[2,3- b]quinoxaline as a new heterocyclic system
2-Substituted-4-methyl-5,13-dihydropyrimido[4',5':5,6][1,4]thiazepino[2,3-b]quinoxalines
(7a-g), derivatives of a new heterocyclic system were synthesized through cyclocondensation of 2,4-dichloro-5-(chloromethyl)-6-methylpyrimidine (3...
Synthesis and characterization of novel 4-(1-(pyrimidin-4-yl)ethyl)-12H-pyrimido[4\\\\\\',5\\\\\\':5,6][1,4]thiazino[2,3-b]quinoxaline derivatives
been reported in the literature.1,3 Herein, we report an efficient one-pot synthetic approach to the synthesis of new 4-(1-(pyrimidin-4-yl)ethyl)-12H-pyrimido[4\\\\\\',5\\\\\\':5,6][1,4]thiazino[2,3-b]quinoxaline derivatives from 5-bromo-4-[1-(5-bromo...
An alternative approach to the synthesis of new pyrimido[5′,4′:5,6][1,4] thiazino[2,3-b]quinoxaline derivatives
An alternative approach to the synthesis of a series of new pyrimido[5′,4′:5,6][1,4]thiazino[2,3-b]quinoxaline derivatives is described. Reaction of 5‑bromo-2,4-dichloro-6-methylpyrimidine and 3‑aminoquinoxaline-2-thiol leads to the key intermediate...
A One-Pot Procedure for the Synthesis of Highly Functionalized Derivatives of a Novel Five-Cyclic Scaffold: Pyrazolo[ 5\\'\\',1\\'\\':2\\',3\\']pyrimido[4\\',5\\':5,6][1,4]thiazino[2,3-b]quinoxaline
Quinoxalines display a broad spectrum of biological and pharmacological activities such as
insecticides, fungicides, herbicides, antibacterial, antimycobacterial, antiprotozoal and anticancer
properties [1]. Furthermore, quinoxaline...
Synthesis, Characterization and In Vitro Antibacterial Evaluation of Novel 4-(1-(Pyrimidin-4-yl)Ethyl)-12H-Pyrimido[4′,5′:5,6][1,4]Thiazino[2,3-b]Quinoxaline Derivatives
A new methodology for the synthesis of 4-(1-(pyrimidin-4-yl)ethyl)-12H-pyrimido[40,50:5,6][1,4]thiazino[2,3-b]quinoxaline derivatives 5a-g was introduced. Condensation of 5-bromo-4-[1-(5-bromo-2,6-dichloropyrimidin-4-yl)ethyl]-2-chloro-6...
Synthesis of Some New 3-Alkylthio Derivatives of 1-Phenyl-1H-[1, 3, 4]thiadiazino[5, 6-b]quinoxalines
2,3-Dichloroquinoxalies; 2-phenylhydrazinecarbodithioate; cyclocondensation; thiadiazinoquinoxalines