Following severe peripheral nerve injury (PNI), regeneration is often insufficient and functional recovery is incomplete. Any agents that limit the spread of neural tissue damage may enhance the nerve regeneration. In this regard, statins have been...

Peripheral nerve injury induces inflammation and oxidative stress, which are the most significant causes of the neuronal death. Alpha Lipoic acid (ɑ-LA) as a potent antioxidant and anti-inflammatory agent may counteract the oxidative...

Background and Objective: In peripheral nerve injuries, electrical stimulations (ES) have been used to accelerate the nerve regeneration. In this study effects of brief voltage-controlled ES on the functional recovery in a transection model...

Purpose Peripheral nerve injury (PNI) is common disorder that represents more than 3 % of all traumatic injury cases. One type of PNI, sciatic nerve injury, leads to considerable motoneuron dysfunction. Because Riluzole is clinically approved...

AIm:

Following severe peripheral nerve injury (PNI), regeneration is often insufficient and functional recovery is incomplete. In this regard, glutamate N-methyl-D-aspartate (NMDA) receptor antagonist such as Memantine have been shown...