-cytometry histogram of treated cells, compared to control, indicating that apoptotic cell death is involved in compounds 4f and 4l induced toxicity. Compounds 4f and 4l exerted cytotoxic and proapototic effects on MCF-7 cell line....

research in the field of colon cancer is focused on introduction of more effective anticancer agents, the goal of present study was to determine cytotoxic effects of AUR in mouse colon adenocarcinoma cells (CT26 cell line). In this regard, AUR was first...

. Herniarin is a member of simple coumarins,

which are a group of common secondary metabolites in plants. In this study, the enhancing

effects of herniarin on cisplatin cytotoxicity were investigated. Cytotoxicity of herniarin on...

Several derivatives of 6-amino-4-aryl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitriles were synthesized via Biginelli type reactionand evaluated fortheir anti-proliferative activity on human breast cancer (MCF-7) and ...

]acridine is a novel synthetic acridine derivative with antibacterial properties. Selective induction of apoptosis in tumor cells is the characteristic of some clinically effective anticancer drugs. In this study, the cytotoxicity and apoptosis inducing effects...

In this study,

we evaluated the cytotoxicity and apoptotic effects of ruthenium, copper, and cobalt

complexes including 3-Hydroxyflavone against human cervix epithelial carcinoma

(HeLa) cell line and using cisplatin as a...

Ribonucleases (RNase) are promising agents for use in cancer therapy. Among the different ribonucleases described to be cytotoxic, pancreatic ribonuclease drew attentions due to similarity with Onconase®. Ruminants produce high levels of pancreatic...

Essential oils, with plant origin, have been of special attention in cancer research during recent years. Despite many reports on cytotoxic effects of plants from genus salvia, the potential application of their extracts in cancer therapy remains...