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نمایش تعداد 1-10 از 12
Isolation, cloning and expression of the Brucella melitensis Omp31 gene
, and the Middle East have currently been listed as high-risk regions. The genus Brucella is classified in at least nine species. Brucella melitensis is the global pathogenic species of Brucella. The outer membrane protein 31, (Omp31) from B. melitensis...
همسانه سازی و بیان ژن پروتین غشای خارجی 31 (Omp31) باکتری بروسلا ملیتنسیسRev1
بیماری بروسلوز به عنوان یک بیماری مشترک بین انسان و دام به واسطه تکثیر باکتری بروسلا در داخل سلولهای پستانداران اتفاق میافتد. Omp31 یکی از پروتئینهای غشای خارجی این باکتری میباشد که به واسطه نقش مهمی که در تحریک سلولهای CD8+ T و CD4+ T دارد میتواند...
Design and Production of a Novel Recombinant Chimeric IL2-Omp31 Antigen against Brucella Infection
Brucellosis is a zoonotic disease in human and animals. Brucella melitensis is one of the most pathogenic
species of Brucella in goat and sheep. Omp31 is an outer membrane protein of Brucella that acts as an
immunogenic protein...
In silico cloning and bioinformatics study of Brucella melitensis Omp31 antigen in different mammalian expression vectors
Brucella melitensis, as a pathogenic gram-negative intracellular bacterium, causes brucellosis in animals and humans. According to literature, the B. melitensis outer membrane protein 31 (Omp31) is considered as an important vaccine candidate...
Cloning and molecular characterization of Omp31 gene from Brucella melitensis Rev 1 strain
recombinant vaccines, based on outer membrane protein (OMP) antigens of Brucella species. The objective of the present study was to clone, analyze the sequence, and predict the epitopes of Omp31 gene as a major B. melitensis antigen. The full-length open...
Immunogenicity evaluation of plasmids encoding Brucella melitensis Omp25 and Omp31 antigens in BALB/c mice
to improve the immunoprotective effects and safety of vaccines against Brucella. This study was designed to evaluate the immunogenicity of DNA vaccines encoding B. melitensis outer membrane proteins (Omp25 and Omp31) against B. melitensis Rev1 in a mouse...
Engineering, Cloning and Expression of DNA Sequence Coding of OMP31 Epitope of Brucella melitensis linked to IL-2 in Escherichia coli
Brucellosis is a zoonetic disease that is caused by Brucella melitensis, which affects human health and animal husbandry industry.
Omp31 is the most exposed outer membrane proteins (OMPs) and is a dominant antigen in smooth strains of B...
The antigenicity performance of divalent recombinant B. melitensis vaccines versus univalent ones
-linked
immunosorbent assay in 12 groups (individual and simultaneous injections of rOMP25 and
rOMP31 in different protein concentrations) and lymphocyte proliferation was measured
using 3–4,5-dimethylthiazol-2-yl2,5-diphenyltetrazolium bromide (MTT) assay based...
Cloning, Molecular Analysis and Epitopes Prediction of Omp31 and Omp25 Genes from B. Melitensis
Brucellosis is a well known infection among domestic animals caused by Brucella bacterium. The objective of the present study was to clone, sequence analysis and epitopes prediction of Omp31 and Omp25 genes as major B. melitensis antigens. Up...
طراحی سازه نوترکیب چند اپی توپی متشکل از 27 آمینواسید آنتی ژن omp31 متصل به سایتو کاین اینترون 2 به منظور تولید واکسن نوترکیب علیه بیماری بروسلوز در گوسفند
اهش صٍ ثش ػٍل صَ یب تت هبلت دس و سَ هب یىی اص ؿبیغ تشیی ثیوبسی بّی هتشن ا ؼًبى دام ث دَ ث ػ اٌَى یىی اص هىلات
التصبدی ث ذْاؿتی جبهؼ یًض هغشح ؼّت. ثیوبسی تت هبلت اصجول ثیوبسی بّی همب مٍ ث دسهبى اػت ث گ ای و دسهبى ...