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    Isolation, cloning and expression of the Brucella melitensis Omp31 gene 

    Type: Journal Paper
    Author : F.Vahedi; احمدفرهاد طالبی; E. Ghorbani; A.M. Behroozikhah; فرج اله شهریاری احمدی; M. Mahmoudi; Farajollah Shahriari Ahmadi
    Year: 2011
    Abstract:

    , and the Middle East have currently been listed as high-risk regions. The genus Brucella is classified in at least nine species. Brucella melitensis is the global pathogenic species of Brucella. The outer membrane protein 31, (Omp31) from B. melitensis...

    همسانه سازی و بیان ژن پروتین غشای خارجی 31 (Omp31) باکتری بروسلا ملیتنسیسRev1 

    Type: Journal Paper
    Author : سهیل یوسفی; مجتبی طهمورث پور; محمدهادی سخاوتی; Soheil Yousefi; Mojtaba Tahmoorespur; Mohammad Hadi Sekhavati
    Year: 2018
    Abstract:

    بیماری بروسلوز به عنوان یک بیماری مشترک بین انسان و دام به واسطه تکثیر باکتری بروسلا در داخل سلول‌های پستانداران اتفاق می‌افتد. Omp31 یکی از پروتئین‌های غشای خارجی این باکتری می‌باشد که به واسطه نقش مهمی که در تحریک سلول‌های CD8+ T و CD4+ T دارد می‌تواند...

    Design and Production of a Novel Recombinant Chimeric IL2-Omp31 Antigen against Brucella Infection 

    Type: Journal Paper
    Author : مهدیه نقوی شهرضا; محمدهادی سخاوتی; مجتبی طهمورث پور; محمدرضا نصیری; Mahdieh Naghavi; Mohammad Hadi Sekhavati; Mojtaba Tahmoorespur; Mohammadreza Nassiri
    Year: 2018
    Abstract:

    Brucellosis is a zoonotic disease in human and animals. Brucella melitensis is one of the most pathogenic

    species of Brucella in goat and sheep. Omp31 is an outer membrane protein of Brucella that acts as an

    immunogenic protein...

    In silico cloning and bioinformatics study of Brucella melitensis Omp31 antigen in different mammalian expression vectors 

    Type: Journal Paper
    Author : مسلم شجاعی; مجتبی طهمورث پور; M. Soltani; محمدهادی سخاوتی; Moslem Shojaei; Mojtaba Tahmoorespur; M. Soltani; Mohammad Hadi Sekhavati
    Year: 2018
    Abstract:

    Brucella melitensis, as a pathogenic gram-negative intracellular bacterium, causes brucellosis in animals and humans. According to literature, the B. melitensis outer membrane protein 31 (Omp31) is considered as an important vaccine candidate...

    Cloning and molecular characterization of Omp31 gene from Brucella melitensis Rev 1 strain 

    Type: Journal Paper
    Author : سهیل یوسفی; محمدهادی سخاوتی; طوبی عباسی دلویی; مجتبی طهمورث پور; Soheil Yousefi; Mohammad Hadi Sekhavati; Tooba Abbassi Daloii; ; سهیل یوسفی; محمدهادی سخاوتی; طوبی عباسی دلویی; مجتبی طهمورث پور; Soheil Yousefi; Mohammad Hadi Sekhavati; Tooba Abbassi Daloii
    Year: 2016
    Abstract:

    recombinant vaccines, based on outer membrane protein (OMP) antigens of Brucella species. The objective of the present study was to clone, analyze the sequence, and predict the epitopes of Omp31 gene as a major B. melitensis antigen. The full-length open...

    Immunogenicity evaluation of plasmids encoding Brucella melitensis Omp25 and Omp31 antigens in BALB/c mice 

    Type: Journal Paper
    Author : مسلم شجاعی; مجتبی طهمورث پور; M. Soltani; محمدهادی سخاوتی; Moslem Shojaei; Mojtaba Tahmoorespur; M. Soltani; Mohammad Hadi Sekhavati
    Year: 2018
    Abstract:

    to improve the immunoprotective effects and safety of vaccines against Brucella. This study was designed to evaluate the immunogenicity of DNA vaccines encoding B. melitensis outer membrane proteins (Omp25 and Omp31) against B. melitensis Rev1 in a mouse...

    Engineering, Cloning and Expression of DNA Sequence Coding of OMP31 Epitope of Brucella melitensis linked to IL-2 in Escherichia coli 

    Type: Journal Paper
    Author : نرگس نظیفی; مجتبی طهمورث پور; محمدهادی سخاوتی; علیرضا حق پرست; M. A. Behroozikhah; narges nazifi; Mojtaba Tahmoorespur; Mohammad Hadi Sekhavati; Alireza Haghparast; M. A. Behroozikhah
    Year: 2018
    Abstract:

    Brucellosis is a zoonetic disease that is caused by Brucella melitensis, which affects human health and animal husbandry industry.

    Omp31 is the most exposed outer membrane proteins (OMPs) and is a dominant antigen in smooth strains of B...

    The antigenicity performance of divalent recombinant B. melitensis vaccines versus univalent ones 

    Type: Journal Paper
    Author : طوبی عباسی دلوئی; سهیل یوسفی; مجتبی طهمورث پور; محمدهادی سخاوتی; Tooba Abbassi Daloii; Soheil Yousefi; Mojtaba Tahmoorespur; Mohammad Hadi Sekhavati
    Year: 2019
    Abstract:

    -linked

    immunosorbent assay in 12 groups (individual and simultaneous injections of rOMP25 and

    rOMP31 in different protein concentrations) and lymphocyte proliferation was measured

    using 3–4,5-dimethylthiazol-2-yl2,5-diphenyltetrazolium bromide (MTT) assay based...

    Cloning, Molecular Analysis and Epitopes Prediction of Omp31 and Omp25 Genes from B. Melitensis 

    Type: Conference Paper
    Author : مجتبی طهمورث پور; محمدهادی سخاوتی; سهیل یوسفی; طوبی عباسی دلوئی; Mojtaba Tahmoorespur; Mohammad Hadi Sekhavati; Soheil Yousefi; Tooba Abbassi Daloii
    Year: 2014
    Abstract:

    Brucellosis is a well known infection among domestic animals caused by Brucella bacterium. The objective of the present study was to clone, sequence analysis and epitopes prediction of Omp31 and Omp25 genes as major B. melitensis antigens. Up...

    طراحی سازه نوترکیب چند اپی توپی متشکل از 27 آمینواسید آنتی ژن omp31 متصل به سایتو کاین اینترون 2 به منظور تولید واکسن نوترکیب علیه بیماری بروسلوز در گوسفند 

    Type: Conference Paper
    Author : مجتبی طهمورث پور; محمدهادی سخاوتی; علیرضا حق پرست; Mojtaba Tahmoorespur; Alireza Haghparast
    Year: 2016
    Abstract:

    اهش صٍ ثش ػٍل صَ یب تت هبلت دس و سَ هب یىی اص ؿبیغ تشیی ثیوبسی بّی هتشن ا ؼًبى دام ث دَ ث ػ اٌَى یىی اص هىلات

    التصبدی ث ذْاؿتی جبهؼ یًض هغشح ؼّت. ثیوبسی تت هبلت اصجول ثیوبسی بّی همب مٍ ث دسهبى اػت ث گ ای و دسهبى ...

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