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RISThe effect of intrathecal administration of ascorbic acid on chemical pain sensation during formalin test in rat
Ascorbic acid (AA) is an essential micronutrient with acidic pH, it can block a variety of membrane bound receptor proteins including the NMDA site receptors which is important in pain signaling…
The effect of intrathecal administration of ascorbic acid on thermal pain sensation
Ascorbic acid (AA) is a water soluble antioxidant vitamin with acidic pH, which is highly concentrated in the brain…
Reduction of chemical pain after intrathecal administration of vitamin K2 in the rats
Introduction . Vitamin K2 is a deriv ative of vitamin K. Effect o f vitamin K2 on the release and function of n eurotransmitters remain ed unknown; b ut du e to the effects of this substance in many neural processes, neu ...
Effects of intrathecal administration of vitamin K2 on formalin induced plantar inflammatory edema in rats
Background and Aim:Menaquinone-4, a derivative of vitamin K is synthesized by intestinal bacteria and in many studies the presence of vitamin K2 (Menaquinone-4) with important functions in the brain at high concentrations ...
Changes in analgesia and hyperalgesia induced by intraperitoneal administration of morphine in the formalin test during intrathecal administration of Menaquinone-4 in rats
Introduction . Various studies su ggest Menaquinone-4 in inhibiting the pain and in flammation. Vitamin K2 in hibits the release of b radykinin and NMDA receptors activity in the spinal co rd can b e con sidered for its ...