The Present research was conducted to evaluate the ability of Deferasirox and Deferiprone (L1) chelators as single and combined therapies in removing lead from biological system. Lead at two doses of 20 (low dose drinking of lead) and 40 mg/kg (high...

in kidneys followed by liver. However, the hypothesis that the two chelators might be more efficient as combined therapy than as single therapy in removing cadmium from the body was considered. In this way, two known chelators deferasirox and deferiprone (L1...

chelators might be more efficient as combined therapy than as single therapy in removing cadmium from the body was considered. In this way, two known chelators Deferasirox (Exjade) and deferiprone (L1) were chosen and tested in the acute rat model. Two...

This study was designed to test the chelation potency of DFO and L1 while given

to animals solely or in combination after vanadium loading. Testing was performed

by using an acute experimental model on rats ...

The Present research was conducted to evaluate the ability of Deferasirox and Deferiprone (L1) chelators as single and combined therapies in removing mercury from biological system. Mercury at two doses of 10 (low dose drinking of mercury) and 30 mg...

An investigation was conducted to evaluate the ability of two chelators, deferasirox and desferrioxamine/Deferiprone in removing Aluminum from biological system....

The present research aimed to characterize the potential efficiency of some chelators after Lead administration for 60 days following two dose levels of Lead to male rats.

In this work, In order to determine the iron(III) spin state effects on the quantum-chemical reactivity indices of iron (III)-deferiprone complexes, density functional theory (DFT) calculations have been performed at the CAM-B3LYP/6-31G level...

that the two chelators might be more efficient as combined therapy than as single therapy in removing cadmium from the body was considered. In this way, two known chelators deferasirox and deferiprone (L1) were chosen and tested in the acute rat model. Two...

Abstract

The hypothesis that two known chelators deferasirox and deferiprone (L1) might be more efficient as combined treatment than as single therapies in removing aluminum from the body was tested in a new acute rat model. Seven...