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RISDecreased migration of human breast cancer cells under Berberine treatment: a possible role of chemokine receptors
of berberine on MCF-7 breast cancer cells. Wound healing assay was used to demonstrate the inhibitory effect of berberine on cell migration. Moreover, real-time quantitative PCR analysis of selected chemokine receptors was performed to determine the probable...
Role of Berberine on molecular markers involved in migration of esophageal cancer cells
progression properties have been reported before. In this study, we investigated the effect of berberine on an esophageal cancer cell line, KYSE-30 with emphasis on its effects on the expression of certain chemokine receptors. The cytotoxic effect of berberine...
Strategies to improve homing of mesenchymal stem cells for greater efficacy in stem cell therapy.
to injured tissues/organs, mediated by interactions of chemokine receptors expressed on the cells and chemokines secreted by the injured tissue. For improvement of directed homing of the cells, many techniques have been developed either to...
Analysis of Chemokine Receptor Gene Expression in Esophageal Cancer Cells Compared with Breast Cancer with Insights into Metastasis
Background: Chemokine receptors have been shown to play an important role in the development and metastatic spread of various malignancies. In this study, the gene expression profile of some key chemokine receptors involved in metastasis has been...
Berberine suppresses migration of MCF-7 breast cancer cells through down-regulation of chemokine receptors
of berberine on MCF-7 breast cancer cells. Wound healing assay was applied to determine the inhibitory effect of berberine on cell migration. Moreover, real-time quantitative PCR analysis of selected chemokine receptors was performed to determine the probable...
CXCR4 and CCR7: Two eligible targets in targeted cancer therapy
in most cases. Recent studies have focused on targeted therapy with more precise identification and targeted attacks to the cancer cells. For this purpose, chemokine receptors are proper targets and among them, CXCR4 and CCR7, with a crucial role in cancer...
Investigating the possible role of Berberine on the metastatic behavior of esophageal cancer cells
. In this study, we have investigated the anti-metastatic effect of berberine on esophageal cancer cell line KYSE-30 and correlate this effect with the decreased expression of some selected chemokine receptors. KYSE-30 cells as esophageal cancer cell line...
Comparative Analysis of Chemokine Receptors Expression in Mesenchymal Stem Cells Derived From Human Bone Marrow and Adipose Tissue
but not least, high
potentials for targeted homing. Homing is the ability of cells in migration and
engraftment to affected tissues. According to recent studies homing is closely related
to the expression of chemokine receptors. Considering...
Comparative Analysis of Chemokine Receptor's Expression in Mesenchymal Stem Cells Derived from Human Bone Marrow and Adipose Tissue
in different characters; however, one of the main properties,
i.e., the expression of chemokine receptors, has been
ignored in these comparisons. In the present study, human
MSCs were derived from bone marrow and adipose tissues...
Chemokine Receptors Expression in MSCs: Comparative Analysis in Different Sources and Passages
potential for isolating MCSs. Here, we compared original MSCs features of adipose tissue (Ad-MSCs) and bone marrow of long-bone (RIA-MSCs) or iliac crest, and the expression of chemokine receptors (including CXCR4, CX3CR1, CXCR6, CXCR2, CCR1 and CCR7...