Objectives: Crocin, an active constituent of saffron (Crocus sativus L.) has widely been known for its antioxidant

properties, which nominate this herbal compound to be of therapeutic value in the neurodegenerative disorders.

Alzheimer...

Alzheimer\\\\\\\\\\\\\\'s disease is a neurodegenerative disorder characterized by slowly progressive dementia, with the hallmark of beta-amyloid peptides (Aβ) as the main constituent of the senile plaques. Aβ 1–42 is one of the enzymatic cleavage...

Alzheimer's is an age-related disease with a hallmark of progressive loss of memory formation followed by a damage in the brain function due to the neural degeneration and extracellular beta-amyloid (Aβ) plaques accumulation. This study examines...

Objectives: Alzheimer\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\'s disease (AD) is a progressive neurodegenerative disorder involving misfolding and aggregation

of a fibrillar 42aa



form of β-amyloid (A β 1–42) peptide, which triggers a...

The proteinase-activated receptors (PARs) are a novel family of G protein-coupled receptors, and their effects in neurodegenerative diseases remain uncertain. Alzheimer s disease (AD) is a neurodegenerative disorder defined by misfolded protein...

Background and Aim : Alzheimer's disease (AD) is a major cause of amnesia and behavioral

injuries in old people that characterized by a progressive loss in cognitive function. This study has

been questioned the protective effect...

Background and Aim : Dysregulated brain insulin signaling has been foregrounded to play an

important role in Alzheimer ’s (AD) pathology. Subclinical icv- STZ model

(intracerebroventricularly streptozotocin injection, icv-STZ) has been...

INTRODUCTON: Alzheimer disease (AD) is a neurodegenerative disorder characterized by a progressive loss of cognitive function. This study aimed to investigate the protective effect of vitamin K2 on toxicity and oxidative damage induced by H2O2 in PC...