Prostate cancer is the second most common cancer in men worldwide. Overexpression of 15-lipoxygenase-1 (15-LOX-1) has been reported in prostate cancer patients. This study aimed to investigate the cytotoxic and anticancer effects of 8...

Prostate cancer is one of the major health threatening cancers in men. At present, the usual clinical treatments of prostate cancer include surgery, radio and chemotherapy. The main chemotherapeutics agents includes steroidal and nonsteroidal anti...

Lipoxygenases are lipid-peroxidizing enzymes that have many important roles in human diseases including cancer. Two different 15-lipoxygenase (15-LOX) enzymes, 15-LOX-1 and 15-LOX-2, are found in humans, with distinct ...

Prostate cancer is a heterogeneous disease that likely results frome a series of genetic events in the prostatic epithelial cells. In spite of major advances in cancer chemotherapy, effective responses have been obtained in a small proportion...

Today, Proton beams are one of the effective tools in treatment of local tumors, such as prostate

tumors. Here, using Monte Carlo MCNPX 2.6 code, voxel phantom of ICRP reference adult man

irradiated by ...

Prostate cancer is one of the most common cancers in the world, which is dependent on age and sex. Prostate cancer incidence increases with age in men and, if not diagnosed and treated in timecan lead to death. Carbostyriles are composed of a large...

chemotherapy drugs such as doxorubicin (DOX) as well as decreasing their dose-limiting side effects.

Overcoming the side effects of doxorubicin (DOX) is a major challenge to the effective treatment of

cancer. ...

BACKGROUND:

Prostate cancer is one of the leading causes of cancer related deaths in males worldwide. Overexpression of 15-lipoxygenase-1 (15-LOX-1) enzyme and high activity of its metabolic pathway is reported to be a driver for prostate...

Prostate cancer is one of the most common cancers affecting males in western

countries. The transition metal complexes as anticancer agentscan interact with

DNA.The present study, the cytotoxic effects of Bis(2-amino-4-methylpyridinium)
<...

O) nanofluids
and ultraviolet A (UVA) irradiation on the cytotoxicity and cellular uptake of doxorubicin (DOX) on human prostate cancer DU145 cells.
Materials and Methods: ZnO nanoparticles were prepared by the solvothermal method and 10% bovine serum...