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RISIn vitro Investigation of Anticancer, Cell-Cycle-Inhibitory, and Apoptosis-Inducing Effects of Diversin, a Natural Prenylated Coumarin, on Bladder Carcinoma Cells
Chemotherapy is one of the main strategies for reducing the rate of cancer progression or, in some
cases, curing the tumour. Since a great number of chemotherapeutic agents are cytotoxic compounds,
i.e.similarly ...
Investigating cytotoxic and anticancer properties of coumarin derivatives containing geranyl groups at different positions on cervical cancer
Coumarin compounds have been known to possess anti-inflammatory, antioxidant, antiallergic, hepatoprotective, antithrombotic, antimicrobial, anti-arrythmic, anti-osteoporosis, antiviral, and anticarcinogenic activities. ...
Ferutinin, an Apoptosis Inducing Terpenoid from Ferula ovina
evidenced by PI staining and DNA laddering. Our results suggest that ferutinin could be considered as
an effective anticancer agent for future in vivo and clinical experiments...
Cytotoxic and anticancer activities of an acridine derivative; 11-chloro-3-methyl-3H-imidazo[4,5-a]acridine on 5637 cells
]acridine is a novel synthetic acridine derivative with antibacterial properties. Selective induction of apoptosis in tumor cells is the characteristic of some clinically effective anticancer drugs. In this study, the cytotoxicity and apoptosis inducing effects...
Benzothiazole Thiourea Derivatives as Anticancer Agents: Design, Synthesis, and Biological Screening
In a systematic effort to identify a potent anticancer agent, we synthesized benzothiazole thiourea
derivatives and examined their cytotoxic activity against five different human and animal cancer cell lines...
A novel red pigment from marine Arthrobacter sp. G20 with specific anticancer activity
/ml. It showed moderate anti-cancer effects on an esophageal cancer cell line, KYSE30, while no inhibition was observed on normal HDF cells. The pigment had no anti-bacterial effects on the four tested strains.
Conclusion: The anti-tumor activity of a...
Investigating the Doxorubicin Adsorption Properties on a Magnetic Nanocomposite Containing Nonporous and Mesoporous silica Layers
regional cancer treatment. In this study, we have been synthesized a core shell nanocmposite(〖Fe〗_3 O_4@〖nSiO〗_2@〖mSiO〗_2) to investigate the adsorption properties of doxorubicin anticancer drug. Thisnanocompositewith core-shell structure contain...
Synthesis and Investigation of Cytotoxic and Anticancer Effects of monoterpenoid stylosin on Prostate Cancer Cells in vitro
monoterpenoid called stylosin and
investigate its cytotoxic and anticancer effects on prostate cancer cell line â€oePC3†and
normal human fibroblast â€oeHFF3†cells in vitro. To do so, stylosin was first synthesized
through esterification...
SYNTHESIS AND IN VITRO ANTICANCER ACTIVITYOF A NOVEL RUTHENIUM AND COPPER(II) COMPLEXS WITH CURCUMIN
comparative standard by MTT
assay. Our studies on the anticancer activity of the complex indicate thise the complex
can inhibit the cellular proliferation in cervix epithelial cancer....
The interaction mode between DNA and salen-Co(III) N,N’-dipyridoxyl (1,4-butanediamine) Shiff-base complex
In this work, we studied the interaction of new salen-co(III) of
N,N\\\\\\'-dipyridoxyl (1,4-butanediamine) Schiff-base complex with DNA by
melthing temperature, fluorescence spectrometry and gel
ele ...