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RISSynthesis and Evaluation of Cytotoxicity of 6-Amino-4-Aryl-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carbonitriles
Year: 2016
Abstract:
Several derivatives of 6-amino-4-aryl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitriles were synthesized via Biginelli type reactionand evaluated fortheir anti-proliferative activity on human breast cancer (MCF-7) and ...
Decreased nitric oxide levels in the hippocampus may play a role in learning and memory deficits in ovariectomized rats treated by a high dose of estradiol
Year: 2012
Abstract:
The effects of a high estradiol dose on memory and on nitric oxide metabolites in hippocampal tissues were investigated. Sham-Est and OVX-Est Groups were treated with 4 mg/kg of estradiol valerate for 12 weeks. Time latency ...