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Evaluation of synthetic zeolites as oral delivery vehicle for anti-inflammatory drugs
Objective(s): In this research, zeolite X and zeolite Y were used as vehicle to prepare intestine targeted oral delivery systems of indomethacin and ibuprofen.
Materials and Methods: A soaking procedure was implemented ...
Modeling and closed-loop control of particle size and initial burst of PLGA biodegradable nanoparticles for targeted drug delivery
An in-house computer code based on artificial intelligence has been developed and applied in modeling and closed-loop optimization of release behavior of Poly(lactic-co-glycolic acid) (PLGA) biodegradable particles. A ...
Use of bacterial ghosts as novel drug delivery systems to improve cancer treatment
Introduction: The bacterial ghost (BG) system represents a novel
and progressive approach in the development of bacterial mediated
cancer immunotherapy. The empty inner space of BGs can be filled
with ...
Mesoporous superparamagnetic hydroxyapatite nanocomposite: A multifunctional platform for synergistic targeted chemo-magnetotherapy
In the present study, the aim was to develop a magneto-responsive nanocomposite for application in drug delivery by the integration of magnetic nanoparticles into an inorganic architecture, hydroxyapatite. The magnetic ...
Preparation and transdermal diffusion evaluation of the prazosin hydrochloride loaded electrospun poly(vinyl alcohol) fiber mats
Critical Issues in Tissue Engineering: Biomaterials, Cell Sources, Angiogenesis, and Drug Delivery Systems
, there are four main challenges in tissue engineering which
need optimization. These include biomaterials, cell sources, vascularization of
engineered tissues, and design of drug delivery systems. Biomaterials and cell
sources should...
Understanding heat dissipation of a remote phosphor layer in an LED system
Injectable hydrogel delivery plus preconditioning of mesenchymal stem cells: exploitation of SDF-1/CXCR4 axis toward enhancing the efficacy of stem cells’ homing
Clinical applications of mesenchymal stem cells (MSCs) rely on their capacity to home and engraft in the appropriate target injury tissues for the long term. However, their homing efficiency has been observed to be very ...