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iron oxide nanoparticles loaded with deferasirox in cancer therapy
two broad strategies in the use of iron chelators in cancer treatment have been explored....
A theoretical study on the electronic structures and equilibrium constants evaluation of Deferasirox iron complexes
chelator in order to reduce iron concentration seems to be
vital. This study presents the density functional theory calculations of the electronic structure and
equilibrium constant for iron-deferasirox (Fe-DFX) complexes in the gas phase...
Chelation of Lead by Combining Deferasirox and Deferiprone in rats
The Present research was conducted to evaluate the ability of Deferasirox and Deferiprone (L1) chelators as single and combined therapies in removing lead from biological system. Lead at two doses of 20 (low dose drinking of lead) and 40 mg/kg (high...
Chelation of Cadmium by Combining Deferasirox and Deferiprone in rats
The present research aimed to characterize the potential efficiency of two chelators after cadmium administration for 60 days following two dose levels of 20 and 40 mg/kg body weight daily to male rats. However, the hypothesis that the two...
THEORETICAL STUDY ON THE MOLECULAR TAUTOMERISM OF THE 5-HYDROXY-2-HYDROXY METHYL PYRIDINE-4(1H)-ONE
5-hydroxy-2-hydroxy methyl pyridine- 4(1H)-one is one of the Hydroxypyridin-4(1H)-one
derivatives which are known in coordination as efficient metal ions chelators. In this work, relative
stabilities of 5-hydroxy-2-hydroxy methyl...
Chelation of Mercury by Combining Deferasirox and Deferiprone in rats
The Present research was conducted to evaluate the ability of Deferasirox and Deferiprone (L1) chelators as single and combined therapies in removing mercury from biological system. Mercury at two doses of 10 (low dose drinking of mercury) and 30 mg...
The effect of thallium on iron, copper and zinc metabolism in rats
. In orther to obviation of iron deficiency anemia that caused by thallium administration, we used the combination therapy with deferasirox and deferiprone (Fig. 1). After administration of chelating agents, thallium levels considerably decreased, the abnormal...
The therapeutic potential of thiamine for treatment of experimentally-induced subacute lead poisoning in sheep
Abstract Lead poisoning remains a serious problem in veterinary and human medicine. A number of lead chelators have been used for treatment of lead intoxication but none of them is completely effective to remove lead from all organs. Therefore...
Using EDTA as a Chelating Agent in Phytoextraction of Cd and Ni from Multi Contaminated Soil and Its Effects on Plant Growth
effective and environmentally sustainable. Enhanced phytoextraction of heavy metals using
chelating agents and agricultural crops is widely discussed as a remediation technique. The
objective of this work, therefore, was to examine the effect of EDTA as a...
Removal of Thallium by Deferasirox in rats as biological model
of one week immediately after thallium administration. After chelation therapy, animals were killed by exsanguinations from abdominal aorta, and then thallium and iron concentrations in various tissues were determined by standard addition method...