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RISA Straightforward Approach for the Synthesis of Novel Derivatives of Benzo [b] pyrazolo [5,1: 2,3] pyrimido [4, 5-e] [1,4] thiazine
Several derivatives of the novel benzo[b]pyrazolo[5′,1′:2,3]pyrimido[4,5-e][1,4]thiazine ring system have been synthesized through the one-pot cyclocondensation of 6-bromo-7-chloro-2-(ethylthio)5-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile (4...
A facile approach for the synthesis of novel benzo[b]pyrazolo[5\\',1\\':2,3]pyrimido[4,5-e][1,4]thiazine derivatives
H exchange inhibitors [3]. Due to the widespread biological activities of fused heterocyclic systems, in this study, we synthesized a novel benzo[b]pyrazolo[5\\',1\\':2,3]pyrimido[4,5e][1,4]thiazine heterocyclic system. In our protocol, the desired compound...
An alternative approach to the synthesis of new pyrimido[5′,4′:5,6][1,4] thiazino[2,3-b]quinoxaline derivatives
An alternative approach to the synthesis of a series of new pyrimido[5′,4′:5,6][1,4]thiazino[2,3-b]quinoxaline derivatives is described. Reaction of 5‑bromo-2,4-dichloro-6-methylpyrimidine and 3‑aminoquinoxaline-2-thiol ...
Synthesis of new derivatives of 10H-benzo[b] pyridazino[3,4-e][1,4]thiazines
New 10H-benzo[b]pyridazino[3,4-e][1,4]thiazines were prepared and evaluated for inhibitory activity against soybean 15-lipoxygenase enzyme. These compounds were synthesized by the sequential treatment of 4-bromo-3,6-dichloropyridazine with 2...