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    8-Farnesyloxycoumarin induces apoptosis in PC-3 prostate cancer cells by inhibition of 15-lipoxygenase-1 enzymatic activity 

    Type: Journal Paper
    Author : سیده مینو حسینی مهر; مریم مقدم متین; Hamid Sadeghian; احمدرضا بهرامی; نسرین کاسب مجاور; minoo hoseiny mehr; Maryam Moghaddam Matin; Ahmad Reza Bahrami; nasrin kaseb mojaver
    Year: 2016
    Abstract:

    Prostate cancer is the second most common cancer in men worldwide. Overexpression of 15-lipoxygenase-1 (15-LOX-1) has been reported in prostate cancer patients. This study aimed to investigate the cytotoxic and anticancer effects of 8...

    studying the anti-cancer effects of 8-farnesyloxycoumarin on Prostate Carcinoma cells in vivo 

    Type: Conference Paper
    Author : سیده مینو حسینی مهر; مریم مقدم متین; احمدرضا بهرامی; H. Sadeghian; صفیه صبورملکی; minoo hoseiny mehr; Maryam Moghaddam Matin; Ahmad Reza Bahrami; saffiyeh saboormaleki
    Year: 2012
    Abstract:

    Lipoxygenases are lipid-peroxidizing enzymes that have many important roles in human diseases including cancer. Two different 15-lipoxygenase (15-LOX) enzymes, 15-LOX-1 and 15-LOX-2, are found in humans, with distinct ...

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