Bovine MHC Class II Structure-Function Relationships: Implications for Vaccine Development
سال
: 2008
چکیده: T cell mediated immunoregulation plays an important role in protective immunity. The central molecular
interaction, which dictates the selection of the specificity of T cells, depends on the interaction between MHC
molecules and peptides derived from degraded antigenic structures. Here, we studied this interaction between
bovine MHC class II molecules and peptides derived from foot and mouth disease virus (FMDV). Progress
during the last decade in our understanding of the mechanisms underlying antigen recognition by T lymphocytes,
opens the possibility to apply this knowledge in new approaches for the development of vaccines.
interaction, which dictates the selection of the specificity of T cells, depends on the interaction between MHC
molecules and peptides derived from degraded antigenic structures. Here, we studied this interaction between
bovine MHC class II molecules and peptides derived from foot and mouth disease virus (FMDV). Progress
during the last decade in our understanding of the mechanisms underlying antigen recognition by T lymphocytes,
opens the possibility to apply this knowledge in new approaches for the development of vaccines.
کلیدواژه(گان): BoLA-DR molecules,MHC-peptide binding assay,T cell epitopes,FMDV
کالکشن
:
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آمار بازدید
Bovine MHC Class II Structure-Function Relationships: Implications for Vaccine Development
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| contributor author | علیرضا حق پرست | en |
| contributor author | Alireza Haghparast | fa |
| date accessioned | 2020-06-06T13:52:15Z | |
| date available | 2020-06-06T13:52:15Z | |
| date copyright | 4/22/2008 | |
| date issued | 2008 | |
| identifier uri | http://libsearch.um.ac.ir:80/fum/handle/fum/3372679 | |
| description abstract | T cell mediated immunoregulation plays an important role in protective immunity. The central molecular interaction, which dictates the selection of the specificity of T cells, depends on the interaction between MHC molecules and peptides derived from degraded antigenic structures. Here, we studied this interaction between bovine MHC class II molecules and peptides derived from foot and mouth disease virus (FMDV). Progress during the last decade in our understanding of the mechanisms underlying antigen recognition by T lymphocytes, opens the possibility to apply this knowledge in new approaches for the development of vaccines. | en |
| language | English | |
| title | Bovine MHC Class II Structure-Function Relationships: Implications for Vaccine Development | en |
| type | Conference Paper | |
| contenttype | External Fulltext | |
| subject keywords | BoLA-DR molecules | en |
| subject keywords | MHC-peptide binding assay | en |
| subject keywords | T cell epitopes | en |
| subject keywords | FMDV | en |
| identifier link | https://profdoc.um.ac.ir/paper-abstract-1008555.html | |
| conference title | XVI Congress of the Mediterranean federation for health and Production of Ruminants | en |
| identifier articleid | 1008555 |