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RISSynthesis and characterisation of new 3-methyl-6-[1-(pyrimidin-4-yl)ethyl]-5Hpyrimido[ 5,4-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazine derivatives
A new series of 3-methyl-6-[1-(pyrimidin-4-yl)ethyl]-5H-pyrimido[5,4-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazine derivatives was synthesised through the condensation reaction of 5-bromo-4-[1-(5-bromo-2,6-dichloropyrimidin ...
A New Multicomponent Synthetic Route to Hexahydropyrido[2,3-d]pyrimidine Derivatives
A new one-pot multicomponent reaction of equimolar amounts of malononitrile and benzaldehyde in ethanol for the synthesis of hexahydropyrido[2,3-d]pyrimidine derivatives through a sequence of Knoevenagel condensation, ...
Novel bis-pyrimidine derivatives: Synthesis and characterization
Introduction: Pyrimidine nucleus has played crucial role in the history of heterocyclic chemistry and has been used extensively as important pharmacophor and synthon in the field of organic chemistry and drug design. ...
Synthesis and characterization of novel 4-(1-(pyrimidin-4-yl)ethyl)-12H-pyrimido[4\\\\\\',5\\\\\\':5,6][1,4]thiazino[2,3-b]quinoxaline derivatives
Development of straightforward and efficient methods for rapid construction of nitrogen and sulfur-containing heterocyclic compounds is an important target in synthetic, medicinal chemistry and in drug design.1 For instance, ...
Regioselective synthesis of new 5H,10H-dipyrimido[2,1-b:4\\\\\\',5\\\\\\'-d][1,3]thiazine as a novel heterocyclic system
Pyrimidothiazines are a class of heterocyclic compounds that have been described as corrosion inhibitor for carbon steel in 1.0 M HCl, Filament temperature sensitive protein Z (FtsZ) inhibitors, 15-LO inhibitory activities, ...
Regioselective synthesis of new 5H,10H-dipyrimido[2,1-b:4′,5′-d][1,3]thiazine: a combined experimental and computational study
Several derivatives of the novel tricyclic system ‘dipyrimido[2,1-
b:4,5-d][1,3]thiazine’ were synthesized via inter- and intramolecular heterocyclization of 2,4-dichloro-5--chloromethyl--6-methylpyrimidine and ...