Search
CSV
RISAn in-situ forming implant formulation of naltrexone with minimum initial burst release using mixture of PLGA copolymers and ethyl heptanoate as an additive: In-vitro, ex-vivo, and in-vivo release evaluation
An in-situ forming implant formulation of naltrexone (NTX) was achieved based on a minimum initial burst release of NTX in the in-vitro release medium using a Box-Behnken design. Variables such as percent of copolymer by ...
Synthesis and DFT study on Hantzsch reaction to produce asymmetrical compounds of 1,4-dihydropyridine derivatives for P-glycoprotein inhibition as anticancer agent
BACKGROUND:
P-glycoprotein (P-gp) causes the efflux of cancer chemotherapy drugs from tumor cells, so its inhibition can be one target for designing and synthesis of new anticancer drugs.
OBJECTIVE:
In ...
Effect of microwave and conventional heating on structural, functional and antioxidant properties of bovine serum albumin-maltodextrin conjugates through Maillard reaction
In present study, effect of conventional heating (CH) and microwave heating (MH) on Maillard reaction (MR)
progression and structural, functional and antioxidant properties of glycated protein was investigated. ...
Preparation and Investigation of Sustained Drug Delivery Systems Using an Injectable, Thermosensitive, In Situ Forming Hydrogel Composed of PLGA-PEG-PLGA
Abstract. In situ gelling systems are very attractive for pharmaceutical applications due to their biode-
gradability and simple manufacturing processes. The synthesis and characterization of thermosensitive
Sustained Delivery of Amphotericin B and Vancomycin Hydrochloride by an Injectable Thermogelling Tri-Block Copolymer
ABSTRACT: Because traditional drug delivery poses many disadvantages such as poor compliance of patients and a drug plasma level variation, novel drug delivery systems containing controlled release drug vehicles become ...