Immunotoxin (IT) therapy is promising approach for targeted cancer therapy with the minimal side

effects. These types of drugs are chimeric proteins with two main parts including death and ligand

domains. ...

Exotoxin A of the Pseudomonas(PEA) is a potently cytotoxic factor for immunotoxins(ITs) designing, via targeting tumor specific antigens as well as inhibition of the protein synthesis. Nonetheless, the molecular size of ...

بیودیزل سوختی پاک، تجدیدپذیر، زیست‌تخریب‌پذیر، عاری از گوگرد و ترکیبات آروماتیک با منابع اولیه مشتق از چربی‌های حیوانی، گیاهی، جلبک‌ها، قارچ‌ها و باکتری‌ها می‌باشند. درمیان این منابع، قارچ‌های روغنی با توجه به قابلیت بالای ...

Background: Human FIX (hFIX) gene transfer into hepatocytes has provided a novel approach for treatment of hemophilia B. To obtain an improved expression of hFIX, the functional hFIX-expressing plasmids with appropriate ...

Accurate prediction of the Cis-regulatory elements encoded within DNA sequences

throughout the genomes and in different regions of a gene is a crucial step towards

understanding the regulatory mechanism of ...

α-sarcin, a fungal ribotoxin, with the appropriate propertise in the size, thermostability, immunogencity, resistance to the proteases as well as cell death induction via ribosome inactivation, is a suitable candidate for ...

سرطان پستان که از مشکلات عمده بهداشت عمومی در جهان می‌باشد، رایج‌ترین سرطان در ‌بین زنان و علت اصلی مرگ و میر ناشی از این نوع از بیماری در این قشر از جامعه است. لذا راهکارهای گسترده‌ای در جهت پیش آگاهی، تشخیص و درمان آن ...

Statistical information about the incidence of cancer malignancies, reminded a high degree of

importance in providing innovative approaches for diagnosis, prevention and treatment of

these type of disease. ...

Cell surface antigens are critical markers for diagnostic and healing of many diseases such as

cancer. In this regard, mesothelin as specixc antigen, with low expression on the normal cells and

over-expression ...