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RISCytotoxic and anticancer activities of an acridine derivative; 11-chloro-3-methyl-3H-imidazo[4,5-a]acridine on 5637 cells
Acridine derivatives are capable of interacting with double-stranded DNA. Some essential enzymes such as DNA topoisomerase I, II and telomerase are the biological targets of these compounds in cancer chemotherapy. ...
Studying the effects of cerium oxide nanoparticles on proliferation of adipose-derived mesenchymal stem cells in vitro
Today, stem cell therapies have been particularly considerd by researchers due to unique abilities of these cells for self-renewal and multipotency. High oxygen levels in culture conditions may result to several cell ...
Preparation of a biological dressing from human amniotic membrane for regenerative studies
Introduction: Skin acts as a physical barrier between body and outside environmentand in case of injuries
it is essential to cover the body with anappropriate dressing. In this regard, biological dressings ...
The effect of platelet-rich plasma on human mesenchymal stem cell-induced bone regeneration of canine alveolar defects with calcium phosphate-based scaffolds
Objective(s): َAutologous bone transplantation known as the “gold standard” to reconstruction of osseous defects has known disadvantages. This study was designed to explore the effect s
of ...
Effects of human adipose-derived stem cells and platelet-rich plasma on healing response of canine alveolar surgical bone defects
Background: Due to the known disadvantages of autologous bone grafting, tissue engineering approaches have become an attractive method for ridge augmentation in dentistry. To the best of our knowledge, this ...
Using paracrine effects of Ad-MSCs on keratinocyte cultivation and fabrication of epidermal sheets for improving clinical applications
Recent advances in wound healing have made cell therapy a potential approach for the treatment of various types of skin defects such as trauma, burns, scars and diabetic leg ulcers. Cultured keratinocytes have been applied ...
Use of cerium oxide nanoparticles: a good candidate to improve skin tissue engineering
Today advancements in nanotechnology have made extensive progress in tissue engineering. Application of cerium oxide nanoparticles -CeO2- has improved regenerative medicine due to their antioxidant properties. In this ...
بررسی اثرات سمیت سلولی 2-(4-متوکسی فنیل)-بنزایمیدازول بر روی سلول های سرطان پستان در شرایط in vitro
مقدمه: با وجود روش های درمانی مختلف برای مقابله با سرطان، بزرگترین مانع در راه درمان سرطان های متاستاتیک مثل سرطان پستان، این است که به طور ذاتی به شیمی درمانی مقاوم هستند و یا در طول شیمی درمانی به دارو مقاوم می شوند. ...
Investigating the possible role of Berberine on the metastatic behavior of esophageal cancer cells
Berberine (BBR) is an isoquinoline alkaloid which can be found in several varieties of plants like Hydrastis canadensis, Berberis aquifolium etc. BBR is one of the components of a famous Chinese herb, Rhizoma coptidis ...
Investigating the Regenerative Potential of Trans- differentiated Adipose-derived Stem Cells (t-ASCs) in Cutaneous Wound Healing
Cutaneous wound healing is a complex type of biological event involving proliferation, differentiation, reprograming, trans/de-differentiation, recruitment, migration, and apoptosis of a number of cells (keratinocytes, ...