Embryonal carcinoma (EC) cells, the stem cells of teratocarcinomas, are the malignant counterparts of pluripotent embryonic stem (ES)

cells, but commonly exhibit a reduced ability to differentiate, presumably because ...

Cancer causes many human deaths worldwide. Much evidence is supporting the idea that

human cancers can be considered as a stem cell disorder. Malignant tumour can be viewed

as an abnormal organ in which a small population...

Cancer stem cells (CSCs) are a subpopulation of

tumour cells that possess the stem cell properties of selfrenewal

and differentiation. Stem cells might be the target

cells responsible for malignant transformation, and tumour...

Cutaneous neoplasms are the most common neoplasm in

dogs. The transforming growth factor (TGF-b) family

has an ambivalent role in cancer progression, as it has

been shown to have both tumour-suppressing and

tumour...