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نمایش تعداد 1-10 از 12
Computational Study on a New Heterocyclic Compound: Structural and Electronic Properties
engineering approach is having an
understanding the control factors of solid-state molecular packing.
Here, we have theoretically explored the new synthesized heterocyclic compound which
was characterized by X-ray single crystal...
Synthesis of a new heterocyclic system Fluoreno[1,2-d]imidazol-10-one
of diazotized oamino-
ketones is a reliable work, which can be extended to the synthesis of other new
heterocyclic compounds....
Synthesis and Docking Analysis of New Heterocyclic System N1, N4-bis ((2-chloroquinolin-3-yl) methylene) benzene-1, 4-diamine as Potential Human AKT1 Inhibitor
In recent years, the chemistry of 2-chloroquinoline-3-carbaldehydes have received
considerable attention owing to their synthetic and effective biological importance which
exhibits a wide variety of biological ...
Synthesis of new functionalized fused heterocyclic compounds derived from isoxazole
Synthesis of new functionalized fused heterocyclic compounds derived from isoxazole...
Synthesis and docking analysis of new heterocyclic system of tetrazolo[5',1':2,3][1,3,4]thiadiazepino [7,6-b]quinolines as aldose reductase inhibitors
Objective(s): In recent years, the chemistry of Tetrazolo[5',1':2,3][1,3,4]thiadiazepino [7,6-b] quinolines have received considerable attention owing to their synthetic and effective biological importance which exhibits ...
Synthesis and docking analysis of new 2-chloro-3-((2,2-dimethylhydrazono) methyl)quinoline derivatives as non-nucleoside human HIV-1 reverse transcriptase inhibitors
In recent years, the chemistry of 2-chloroquinoline-3-carbaldehydeshave received considerable attention owing to their synthetic and effective biological importance which exhibits a wide variety of biological activity, and ...
Synthesis of Oxazolo[5,4-d][1,2,4]triazolo[4,3-a]pyrimidines as a New Class of Heterocyclic Compounds
Several new derivatives of oxazolo[5,4-d]pyrimidine (3a–h) have been synthesized through the reaction
of 2,4-dichloro-6-methyl-5-nitropyrimidine (2) with aryl carboxylic acids in refluxing POCl. Further treatment of ...
15-Lipoxygenase inhibitors: A patent review
Introduction: 15-Lipoxygenases (15-LOXes) are a family of iron-containingproteins that have the capability for unsaturated fatty acid peroxidation inanimals and plants. Two types of the enzyme, 15-LOX-1 and 15-LOX-2, ...
Synthesis of novel heterocycle systems: 6,8-dimethyl-2-(methylsulfanyl-4-amino-substituted pyrimido[4′,5′:3,4]pyrazolo[1,5-a]pyrimidine and 9,11-dimethyl-5-(methylsulfanyl)pyrimido[2′,1′:5,1]pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
The novel heterocyclic pyrimidopyrazolopyrimidine system was synthesised through cyclisation of 4‑hydrazinyl-2,6-bis(methylthio)pyrimidine-5-carbonitrile with acetylacetone in high yield. Also, two other tetracyclic systems ...
Synthesis of new derivatives of pyrimido[4,5-c] pyridazine
Pyridazines and pyrimidine derivatives are important class of heterocyclic compounds in medicinal chemistry especially in the treatment of diseases like the central nervous systemand the cardiovascular system [1]. In continuation of our previous...