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Author : Oleg Fedorov; Kilian Huber; Andreas Eisenreich; Panagis Filippakopoulos; Oliver King; Alex N. Bullock; Damian Szklarczyk; Lars J. Jensen; Doriano Fabbro; Jörg Trappe; Ursula Rauch; Franz Bracher; Stefan Knapp

Publisher: Elsevier Science

Year: 2011

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Perspective on computational and structural aspects of kinase discovery from IPK2014

Type: Journal Paper

Author : Eric Martin; Stefan Knapp; Richard A. Engh; Henrik Moebitz; Thibault Varin; Benoit Roux; Jens Meiler; Valerio Berdini; Alexander Baumann; Michal Vieth

Year: 2015

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Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

Type: Journal Paper

Author : Xianming Deng; Jonathan M. Elkins; Jinwei Zhang; Qingkai Yang; Tatiana Erazo; Nestor Gomez; Hwan Geun Choi; Jinhua Wang; Nicolas Dzamko; Jiing-Dwan Lee; Taebo Sim; NamDoo Kim; Dario R. Alessi; Jose M. Lizcano; Stefan Knapp; Nathanael S. Gray

Year: 2013

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Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization

Type: Journal Paper

Author : Jakob Gebel; Laura M Luh; Daniel Coutandin; Christian Osterburg; Frank Löhr; Birgit Schäfer; Ann-Sophie Frombach; Manuela Sumyk; Lena Buchner; Tobias Krojer; Eidarus Salah; Sebastian Mathea; Peter Güntert; Stefan Knapp; Volker Dötsch

Year: 2016

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Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

Type: Journal Paper

Author : Panagis Filippakopoulos; Sarah Picaud; Maria Mangos; Tracy Keates; Jean-Philippe Lambert; Dalia Barsyte-Lovejoy; Ildiko Felletar; Rudolf Volkmer; Susanne Müller; Tony Pawson; Anne-Claude Gingras; Cheryl H. Arrowsmith; Stefan Knapp

Publisher: Elsevier Science

Year: 2012

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Small-Molecule Inhibition of BRDT for Male Contraception

Type: Journal Paper

Author : Martin M. Matzuk; Michael R. McKeown; Panagis Filippakopoulos; Qinglei Li; Lang Ma; Julio E. Agno; Madeleine E. Lemieux; Sarah Picaud; Richard N. Yu; Jun Qi; Stefan Knapp; James E. Bradner

Year: 2012

[1,2,4]Triazolo[4,3- a ]phthalazines: Inhibitors of Diverse Bromodomains

Type: Journal Paper

Author : Oleg Fedorov; Hannah Lingard; Chris Wells; Octovia P. Monteiro; Sarah Picaud; Tracy Keates; Clarence Yapp; Martin Philpott; Sarah J. Martin; Ildiko Felletar; Brian D. Marsden; Panagis Filippakopoulos; Susanne Müller; Stefan Knapp; Paul E. Brennan

Year: 2014

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Targeting bromodomains: epigenetic readers of lysine acetylation

The ins and outs of selective kinase inhibitor development

Insights for the development of specific kinase inhibitors by targeted structural genomics

Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing

Perspective on computational and structural aspects of kinase discovery from IPK2014

Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

Small-Molecule Inhibition of BRDT for Male Contraception

[1,2,4]Triazolo[4,3- a ]phthalazines: Inhibitors of Diverse Bromodomains

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Targeting bromodomains: epigenetic readers of lysine acetylation

The ins and outs of selective kinase inhibitor development

Insights for the development of specific kinase inhibitors by targeted structural genomics

Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing

Perspective on computational and structural aspects of kinase discovery from IPK2014

Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

Small-Molecule Inhibition of BRDT for Male Contraception

[1,2,4]Triazolo[4,3- a ]phthalazines: Inhibitors of Diverse Bromodomains