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Neuroinflammation and Endoplasmic Reticulum Stress Are Coregulated by Crocin To Prevent Demyelination and Neurodegeneration
Year: 2011
Abstract:
Endoplasmic reticulum (ER) stress is a homeostatic mechanism, which is used by cells to adapt to intercellular and intracellular
changes. Moreover, ER stress is closely linked to inflammatory pathways.We hypothesized ...
Proteinase activated receptor-2 exerts protective and pathogenic cell-type specific effects in Alzheimer s disease
Year: 2007
Abstract:
The proteinase-activated receptors (PARs) are a novel family of G protein-coupled receptors, and their effects in neurodegenerative diseases remain uncertain. Alzheimer s disease (AD) is a neurodegenerative disorder defined ...