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Salts and Cocrystals of Antidiabetic Drugs, Gliclazide, Tolbutamide and Glipizide: Solubility Enhancements through Drug-Coformer Interactions
Gliclazide (GCZ), tolbutamide (TOL) and glipizide (GPZ) are BCS class IIantidiabetic drugs with poor aqueous solubility. Multicomponent solid forms, salts, and cocrystals of GCZ were ...
Orientation-dependent conformational polymorphs in two similar pyridine/pyrazine phenolic esters
On the basis of crystal engineering, two similar esters of phenyl pyridine-2-carboxylate (I) and phenyl
pyrazine-2-carboxylate (II) were designed and synthesized. The compounds were characterized using FTIR, mass ...
Conformational variation of ligands in mercury halide complexes; high and low Z′ structures
In this study, five new mercury halide complexes of [Hg(LPy)2Cl2] (1), [Hg(LPy)2Br2] (2), [Hg(LPy)2I2] (3), [Hg(LPz)2Cl2] (4) and [Hg(LPz)2Br2] (5) in which LPy is a phenyl pyridine-2-carboxylate and LPz is a phenyl ...
Exploration of relative π-electron localization in naphthalene aromatic rings by C–H⋯π interactions: experimental evidence, computational criteria, and database analysis
Based on the crystal engineering concept, four new esters containing α and β-substituted naphthalene rings were designed, synthesized and fully characterized. The crystal structure analysis of the designed molecules revealed ...
حل عددی معادله شرودینگر برای دوترون در چاه پتانسیل یوکاوا
بررسیهای انجام گرفته نشان می دهد که دوترون ترکیبی از 96% حالت l=0 و 4% در حالت l=2 است هدف از این مقاله تائید مسئله فوق در چاه پتانسیل یوکاوا است.
How CH‐based interacions affect the packing of mercury halide complexes
In the presence study, the organic ligand (2-naphtyl pyridine-2-carboxylate) (L), which was designed to make exclusive C‒H based interactions, was employed for the synthesis of three new mercury (II) halide complexes, ...
Can substitution effect control the metal-ligand polymerization?!
On the base of our previous studies due to the presence of halides in our complexes there is strong probability for obtaining coordination polymers. Crystal engineering well-defined as the understanding of intermolecular ...