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RISEvidences for Interconvertability Potency of Germ Cell Factors Induced-MEFs to Neural-Like Cells
Background: Mammalian germ cell genome undergoes a massive epigenetic modification during fetal development and spatio-temporal regulated gene expression plays a critical role in primordial germ cell (PGC) destiny. Method: We designed a...
The CDK inhibitor p27enhances neural differentiation in pluripotent NTERA2 human EC cells, but does
Embryonal carcinoma (EC) cells, the stem cells of teratocarcinomas, are the malignant counterparts of pluripotent embryonic stem (ES)
cells, but commonly exhibit a reduced ability to differentiate, presumably because ...
Isolation, Culture and Characterization of Chicken Primordial Germ Cells
could be achieved in different ways, including application of primordial germ cells. Primordial germ cells are progenitor of sperm and ovum. These cells are round, with a big nucleus and a cytoplasm with lipid and glycogen particles. The first step...
Ultrastructure of ovarian germ cells in the ostrich (Struthio camelus) embryo
In this study, the ultrastructural development of germ cells in the ostrich embryo was analysed. The
nuclear organisation and morphological characteristics of cytoplasm in the developing germ cells, on
embryonic days 20, 26, and 36...
Study of the expression of a pluripotency-associated Long non coding RNA in Embryonic germ cells
Although a wealth of information currently exists for genetic networks involved in pluripotency of mouse embryonic stem cells mESCs, less is known about mouse embryonic germ cells (mEGCs). Especially To date more studies have focused almost...
Expression dynamics of pluripotency genes in chicken primordial germ cells before and after colonization of the genital ridges
Mammalian species utilize an inductive mechanism of germ cell specification, diverting the fate of some of somatic cells toward pluripotency and germ-cell totipotency. It is not known if avian species utilize a similar mechanism nor if, analogous...
Isolation and characterization of differentially expressed genes in invasive and non-invasive immortalized murine male germ cells in vitro
In an attempt to elucidate the potential of premeiotic male germ cells to malignant transformation both the invasiveness and the differential gene expression of several putative tumor markers of the spermatogonia-derived cell line GC...
The potential for archiving and reconstituting valuable strains of turkey (Meleagris gallopavo) using primordial germ cells
Morphological development of testes in ostrich embryo and newly hatched ostrich chick
distinguishable from kidney in texture and color. In 20-d-old embryos aggregations of Sertoli cells corralled some primordial germ cells (PGCs). In 26-d-old embryos Sertoli cells aggregations were more regular and more similar to shape of cord. PGCs are clearly...
Meiotic initiation in chicken germ cells is regulated by Cyp26b1 and mesonephros
Our knowledge of mechanisms involved in the meiosis of chicken germ cells is very limited. In mammalian fetal ovaries, the onset of meiosis is dependent on retinoic acid and subsequent upregulation of the Stra8 gene. To clarify the mechanism...