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Efficient TALEN-Mediated Mutagenesis on a Highly Conserved Region of Myostatin Gene in Mouse Embryonic Stem Cells
Year: 2014
Abstract:
Myostatin is a negative regulator of muscle growth. The naturally occurring mutations of myostatin gene (MSTN) are strongly associated with meat production traits in livestock. Thus far, many attempts have been made to ...
Application of phiC31 integrase system in stem cells biology and technology: a review
Year: 2018
Abstract:
medicine. Gene targeting plays a pivotal role in creating modified stem cells,
which are considered the mainstay in regenerative medicine. The phiC31 integrase system, as a sitespecific recombinase, could be a straightforward and efficient approach...