An alternativemechanism of cell-to-cell communication via extracellular

vesicles -EVs- has recently raised increasing attention. EVs

are spherical structures comprising exosomes and microvesicles,

capable of transferring...

for cellular exchanging. Here, a cell-free therapy using engineered exosomes which are non-toxic, non-immunogenic, and capable for doing targeted delivery in challenging situation such as Blood Brain Barrier (BBB) are introduced as nano carriers...

well-known microRNA, overexpressed in almost all cancer types, including brain tumors. It targets several genes with vital roles in cellular pathways involve in proliferation, invasion and metastatic behavior. Exosomes are 30-100 nm extracellular...

Extracellular vesicles are known as actual intermediaries of intercellular communications, such as biological signals and cargo transfer between different cells. A variety of cells release the exosomes as nanovesicular bodies. Exosomes contain...