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RISImmunogenicity evaluation of plasmids encoding Brucella melitensis Omp25 and Omp31 antigens in BALB/c mice
to improve the immunoprotective effects and safety of vaccines against Brucella. This study was designed to evaluate the immunogenicity of DNA vaccines encoding B. melitensis outer membrane proteins (Omp25 and Omp31) against B. melitensis Rev1 in a mouse...
The antigenicity performance of divalent recombinant B. melitensis vaccines versus univalent ones
-linked
immunosorbent assay in 12 groups (individual and simultaneous injections of rOMP25 and
rOMP31 in different protein concentrations) and lymphocyte proliferation was measured
using 3–4,5-dimethylthiazol-2-yl2,5-diphenyltetrazolium bromide (MTT) assay based...
Cloning, Molecular Analysis and Epitopes Prediction of Omp31 and Omp25 Genes from B. Melitensis
Brucellosis is a well known infection among domestic animals caused by Brucella bacterium. The objective of the present study was to clone, sequence analysis and epitopes prediction of Omp31 and Omp25 genes as major B. melitensis antigens. Up...
Inhibition of toll like receptor 2 mediated NF خ؛B activation in vero cells with herpesvirus of Turkeys
B and T‐Cell Epitope Prediction of the OMP25 Antigen for Developing Brucella melitensis Vaccines for Sheep
the use of recombinant vaccines based on Brucella outer mem-brane protein (OMP) antigens. In the present study, a wide range of on-line prediction software was used to predict B and T-cells epitopes, secondary and tertiary tructure and antigenicity OMP25...
Isolation, cloning and expression of the Brucella melitensis Omp31 gene
, and the Middle East have currently been listed as high-risk regions. The genus Brucella is classified in at least nine species. Brucella melitensis is the global pathogenic species of Brucella. The outer membrane protein 31, (Omp31) from B. melitensis...
همسانه سازی و بیان ژن پروتین غشای خارجی 31 (Omp31) باکتری بروسلا ملیتنسیسRev1
بیماری بروسلوز به عنوان یک بیماری مشترک بین انسان و دام به واسطه تکثیر باکتری بروسلا در داخل سلول‌های پستانداران اتفاق می‌افتد. Omp31 یکی از پروتئین‌های غشای خارجی این باکتری میباشد که به واسطه نقش مهمی که در تحریک سلول‌های CD8+ T و CD4+ T دارد می‌تواند...
Design and Production of a Novel Recombinant Chimeric IL2-Omp31 Antigen against Brucella Infection
Brucellosis is a zoonotic disease in human and animals. Brucella melitensis is one of the most pathogenic
species of Brucella in goat and sheep. Omp31 is an outer membrane protein of Brucella that acts as an
immunogenic protein...
In silico cloning and bioinformatics study of Brucella melitensis Omp31 antigen in different mammalian expression vectors
Brucella melitensis, as a pathogenic gram-negative intracellular bacterium, causes brucellosis in animals and humans. According to literature, the B. melitensis outer membrane protein 31 (Omp31) is considered as an important vaccine candidate...
کلونینگ، تعیین توالی و بررسی فیلوژنتیکی توالی ژن OMP25 از باکتری بروسلا ملیتنسیس
پروتئین OMP55 یکی از آنتیژنهای خارج غشائی باکتری بروسلا است که دارای ویژگیهای آنتیژنیک میباشد. این آنتیژن یکی از
آنتیژنهای اصلی است که نقش مهمی در ایجاد بیماری بروسللوز و همچنلین زنلده ملا نی بلاکتری بروسللا دارد . در ایلن ماالعله ژن
OMP...