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Metal-Free Debromination of 5-Bromopyrimidine Derivatives Using DMF/Trialkylamine as the Hydrogen Source
Year: 2018
Abstract:
Attempted heterocyclization of 5-bromo-2,4-diamino-6-substituted pyrimidines in a mixture of DMF and trialkylamines (Et3N or N,N-diisopropylethylamine) under mild conditions, led to the formation of new dehalogenated ...